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Luca GIANNETTI
Professore Associato
Dipartimento Chirurgico, Medico, Odontoiatrico e di Scienze Morfologiche con interesse Trapiantologico, Oncologico e di Medicina Rigenerativa
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Pubblicazioni
2022
- Effect of Orthophosphoric Acid and Er:YAG Laser Etching on Micro-shear Bond Strength to Enamel: An In Vitro Pilot Study
[Articolo su rivista]
Zanigni, Ludovica; Checchi, Vittorio; Davide Pugliese, Bruno; Josic, Uros; Mazzitelli, Claudia; Giannetti, Luca; Breschi, Lorenzo; Nucci, Cesare
abstract
Background: Dental conditioning is one of the most important phases during enamel bonding procedures to obtain clean surfaces, smear layer removal with collagen active sites and hydroxyapatite exposure. Objective: The aim of this study was to compare the micro-shear bond strength (μSBS) of different adhesive systems after two different etching techniques: 37% orthophosphoric acid (H3PO4) and Er:YAG laser. Methods:
Ninety permanent extracted molars were embedded into epoxy resin blocks and sectioned longitudinally. Specimens were randomly assigned to one of the following groups (n=30), depending on the etching protocol: 37% H3PO4 for 30 s (Group 1), Er:YAG laser 100mJ-10Hz (Group 2), and Er:YAG laser 100mJ-10Hz followed by 37% H3PO4 for 30 s (Group 3). Each group was further divided into two subgroups depending on the bonding agent used on enamel (n=15): A) EE-Bond (Tokuyama) and B) Peak universal (Ultradent). A two-way analysis of variance (two-way ANOVA) was conducted and the level of significance was set to p=0.05. Results: The etching procedure was a significant factor influencing the results (p=0.006), while no differences were observed for the two adhesive systems tested (p>0.05). Group 3 recorded the highest bond strength values, according to the following sequel: Group 3 < Group 2 < Group 1 < 0.05. Conclusion: The combination of phosphoric acid etching with Er:YAG laser provided the most favourable bond strength to enamel. Further morphological studies are currently ongoing.
2022
- The occlusal precision of milled versus printed provisional crowns
[Articolo su rivista]
Giannetti, L.; Apponi, R.; Mordini, L.; Presti, S.; Breschi, L.; Mintrone, F.
abstract
Objectives: The aim of this study was to compare the occlusal precision of computer-aided-design/ computer-assisted-manufacturing (CAD/CAM) milled versus 3D printed polymethylmethacrylate (PMMA) temporary prosthetic crowns, starting from the same digital CAD design. Materials and methods: The study sample included 34 patients presenting 34 premolars in need of prosthetic rehabilitation: a total of 68 temporary crowns were manufactured, 34 of which milled and 34 printed. Immediately after manufacturing, the milled and printed provisionals were scanned with a desktop scanner (E1, 3Shape) to obtain STL files, that were superimposed to the original CAD design in order to identify the occlusal trueness (Analysis A). A second occlusal comparison was performed by scanning both kind of provisional after being placed intraorally with Trios scanner (3 Shape); intraoral scans were obtained in order to compare STL files of provisionals before and after occlusal adjustments (Analysis B). The occlusal trueness was identified at three reference points, P1 (vestibular cusp), P2 (palatal / lingual cusp), P3 (central fossa). The statistical analysis was performed using the R 3.4.3 statistical software (The R Foundation for Statistical Computing), with a significance level of p <0.05. Results: Overall, the printed crowns showed lower occlusal differences than the milled crowns, when compared to the CAD design file, with a statistically significant difference in P1 (difference of 0.025 ± 0.046 mm), P2 (difference of 0.027 ± 0 0.044 mm) and P3 ( difference of 0.018 ± 0.050) for Analysis A (p <0.05). In the Analysis B the direct comparison between the degree of average difference between the pre-adjustment and the post-occlusal adjustment of the milled and printed crowns shows that the printed crowns have lower occlusal mean difference values in all three points compared to the milled ones (difference of 0.146 ± 0.273 mm in P1, 0.285 ± 0.360 mm in P2 and 0.257 ± 0.277 mm in P3). Conclusions: Within the limitation of this study, the data obtained showed a better occlusal surface dimensional accuracy of the 3D printed provisional crowns, when compared to the milled ones. Comparing the results obtained, it is possible to assume that the intraoral scans also had a contribution to occlusion, beside the manufacturing method. 3D printing can be successfully applied for manufacturing temporary PMMA crowns.
2021
- Comparative evaluation of the penetration depth into dentinal tubules of three endodontic irrigants
[Articolo su rivista]
Giardino, L.; Pedullà, E.; Cavani, F.; Bisciotti, F.; Giannetti, L.; Checchi, V.; Angerame, D.; Consolo, U.; Generali, L.
abstract
This study aimed to examine the penetration depth into dentinal tubules of some chelating agents. The 17% EDTA and two preparations containing surfactants (Smear Clear, Bioakt Endo) were tested. Surface tension and liquid viscosity were measured using a Dynamic Contact Angle Analyzer and a Haake rotational rheometer. To measure the penetration depth inside dentinal tubules, thirty maxillary central incisors were selected from a pool of extracted human permanent teeth and allocated to three experimental groups (10 samples each), as well as were mechanically shaped and cleansed with 5.25% NaOCl, followed by each of the chelators being labeled with 0.1 wt % Rhodamine B according to final irrigation protocol established. The samples were embedded in an epoxy resin, after which 200 μm thick transverse sections were obtained at 2, 5, and 8 mm from the apex with a saw microtome. The specimens were then observed using a confocal laser microscope (CLSM) and the penetration of the labeled solution was measured in every third of each sample. Statistical analysis was performed using ANOVA or Kruskal–Wallis tests according to the distribution of data, evaluated with the Shapiro–Wilk normality test. Viscosity and surface tension tests have shown that BioAKT Endo has the lowest values compared to EDTA and Smear Clear. The medium penetration depth did not significantly differ among the three irrigants, while it increased considerably from the apical to the coronal level in all groups. Additionally, the maximum penetration depth increased significantly from the apical to coronal level, while among groups, BioAKT Endo showed the highest values at the apical and middle level compared to the other irrigants. No significant differences were observed among the three groups in medium and maximum penetration depths when the entire root was considered. New irrigants containing surfactants show reduced surface tension and, in one case (BioAKT Endo), viscosity. The lowering of the surface tension allows for better penetration of liquids into dentinal tubules than EDTA alone, thus improving the cleaning of the root canal system.
2021
- Hypersensitivity in molar incisor hypomineralization: Superficial infiltration treatment
[Articolo su rivista]
Diago, A. M. D.; Cadenaro, M.; Ricchiuto, R.; Banchelli, F.; Spinas, E.; Checchi, V.; Giannetti, L.
abstract
To date, there are no standardized protocols available in the literature for hypersensitivity treatment in molar incisor hypomineralization (MIH) patients. The aim of this study was to evaluate the efficacy of erosion–infiltration treatments with resin in children with a strong hypersensitivity and also to develop a minimally invasive diagnostic–therapeutic pathway for young MIH patients. Patients with clinical signs of MIH were enrolled according to international guidelines. A total of 42 patients (8–14 years old) with sensitivity of at least one molar and patients with post eruptive enamel fractures, but without dentin involvement or cavitated carious lesions were selected. A single superficial infiltration treatment with ICON (DMG, Germany) was performed with a modified etching technique. Sensitivity was tested with the Schiff Scale and Wong Baker Face Scale and was repeated at 12 months follow‐up. All patients reported lower sensitivity values at the end of the treatment. Significant differences of sensitivity according to the Schiff scale were reported between T0 and all subsequent follow‐ups, p < 0.05. The treatment of erosion infiltration with ICON resin is a minimally invasive preventive treatment that significantly improves the problem of hypersensitivity in permanent molars with MIH.
2021
- Lymphoplasmacytic plaque effectively treated with imiquimod
[Articolo su rivista]
Maurelli, M.; Colato, C.; Giannetti, L.; Girolomoni, G.
abstract
2021
- Pulp canal obliteration after extrusive and lateral luxation in young permanent teeth: A scoping review
[Articolo su rivista]
Spinas, E.; Deias, M.; Mameli, A.; Giannetti, L.
abstract
AIM: In the literature, no single therapeutic approach is preferred for treating dental pulp responses such as pulp canal obliteration (PCO). Some authors still recommend preventive endodontic treatment, whereas others choose not to intervene, to avoid causing possible iatrogenic complications. This review was conducted to explore, in the current scientific literature, the degree of knowledge concerning the onset and development of PCO and pulp necrosis (PN) following dental trauma (i.e. extrusive luxation and lateral luxation) in children and young adults (6-20 years). The authors also evaluated whether and to what extent the stage of dental root development at the time of traumatic dental injury (TDI) influences these pulp responses, and whether PN can arise in teeth already affected by PCO. MATERIALS AND METHODS The literature search was carried out during the period October 2019 to January 2020, using the following databases: PubMed/MEDLINE, SCOPUS and Web of Science. Articles in English reporting on young patients with PCO or PN in permanent teeth affected by trauma were included. Theresearch, whose questions were summarised according to the PICO method, considered the following aspects: patient age, type of TDI, stage of root development, initial treatment, presence of calcification or necrosis, time to onset of the two outcomes (PCO and PN), and duration of follow-up. The articles found were evaluated by two reviewers; in the event of disagreement regarding the inclusion of an article, a third reviewer was called upon to decide. RESULTS: The initial screening of the databases, using the selected search keywords, yielded a total of 343 articles. After exclusion of duplicates and articles not meeting the inclusion criteria, 11 articles remained. Of these, only four completely met the inclusion criteria. Closer analysis of these four publications revealed that they would not easily yield standardised sets of clinical data that might be homogenised in order to produce clear meta-analytical data. Hence the need to limit the data collected to the following seven items: number and type of injuries, type of initial intervention, duration of follow-up, main pulp responses, number and type of pulp responses. CONCLUSIONS: PCO is a physiological pulp response associated with a traumatic event, usually a luxation injury. It is diagnosed on the basis of combined radiographic and clinical-anamnesticdata. Signs of PCO start to appear at around one year after the traumatic event, and its development reaches completion by about five years post-trauma. PN, on the other hand, is clearly apparent within the first year. Endodontic treatment, be it carried out as a preventive measure or following detection of PCO, is inappropriate and can cause serious iatrogenic damage. Treatment is indicated only in cases of definite PN.
2021
- Recurrent aphthous stomatitis: Treatment and management
[Articolo su rivista]
Manfredini, M.; Guida, S.; Giovani, M.; Lippolis, N.; Spinas, E.; Farnetani, F.; Dattola, A.; Di Matteo, E.; Pellacani, G.; Giannetti, L.
abstract
Background: Recurrent aphthous stomatitis consists of the presence of abrasions or ulcerations located on mucosae (oral or genital). Objectives: The aim of this article is to review the current literature providing the main causes related to recurrent aphthous stomatitis and insights into treatment and management of this clinical condition Methods: Articles matching terms that correlated with "recurrent aphthous stomatitis"were searched on PubMed, EMBASE, and Cochrane Library and selected according to their pertinence. Results: Several forms of aphthous stomatitis have been described, based on the extent (minor, major), morphology (herpetiform) and associations to other signs (Behçet syndrome or more complex inflammatory syndromes). Topical as well as systemic treatments have been described to obtain a faster remission of the aphthosis or to reduce associated symptoms such as pain. Conclusions: Recurrent aphthous stomatitis can have a mild-to-severe clinical appearance, being mainly localized on the oral mucosa or at the level of the genital area. Different strategies have been described so far for its management and treatment.
2021
- Rehabilitation of a patient with mini-implants after avulsion of the upper incisors: A 13-year follow up
[Articolo su rivista]
Giannetti, L.; Apponi, R.; Murri Dello Diago, A.; Mintrone, F.
abstract
Treatment following avulsion of a tooth in the growing patient requires a complex multidisciplinary therapeutic approach for the clinical team. The literature offers different therapeutic solutions following the avulsion of one or more teeth, but unfortunately all of them have negative repercussions on the patients' life quality, they involve long treatment plans, they are not always feasible, and they have limits. Alternatively, a new treatment concept that uses mini-implants can be considered and is presented with its rationale, clinical steps and 13 years of follow up of one case.
2021
- Sport and dental traumatology: Surgical solutions and prevention
[Articolo su rivista]
Mordini, L.; Lee, P.; Lazaro, R.; Biagi, R.; Giannetti, L.
abstract
Trauma is a worldwide cause of millions of deaths and severe injuries every year, all over the world. Despite the limited extension of the oral region compared to the whole body, dental and oral injuries account for a fairly high percentage of all body traumas. Among head and neck traumas, dental and facial injuries are highly correlated to sport activities, and their management can be a real challenge for practitioners of any specialty. In case of trauma directed to periodontal structures, restorative and endodontic solutions may not be sufficient to achieve a definitive and long-lasting treatment. This article aims to illustrate surgical options and appliances to prevent dental injuries that may be available to the clinicians treating dental trauma involving oral soft and hard tissues.
2021
- Therapy of autoimmune mouth bullous disease: 2020 review
[Articolo su rivista]
Giannetti, L.; Murri Dello Diago, A.
abstract
Most diseases of oral mucosa are either autoimmune in nature or are the results of immunologically mediated events. The diseases with autoimmune pathogenesis are namely pemphigus and pemphigoid; the oral involvement is frequent or regularly observed in these diseases. The treatments with traditional drugs or biologic agents or combinations of these molecules are employed in clinical practice. New therapeutic targets aim to provide new treatment strategies that may go beyond nonspecific immunosuppression.
2021
- Use of orthodontic methods in the treatment of dental luxations: A scoping review
[Articolo su rivista]
Spinas, E.; Pipi, L.; Mezzena, S.; Giannetti, L.
abstract
(1) Background: Treating dental luxation injuries is challenging for the clinician. Dental luxations account for 18–33% of injuries to permanent teeth and can be addressed using different therapeutic approaches. The present work was conducted with two aims: (i) to evaluate, through a scoping review, current knowledge of the orthodontic methods (repositioning and stabilization splinting) that can be used at the time of the trauma, and (ii) to investigate the frequency and type of pulp consequences arising after these traumatic injuries. (2) Methods: The literature search was conducted in the period June 2020–December 2020 using the PubMed/MEDLINE, SCOPUS and Web of Science databases. The research questions were formulated according to the PICO (Population, Intervention, Comparison, Outcomes) method and considered the following aspects: type of luxation injury and stage of root development; use of orthodontic repositioning and splinting techniques; frequency and type of pulp consequences; and compliance of treatments with international guidelines. (3) Results: The initial screening of the databases, using the selected search keywords, yielded a total of 587 articles, just 8 fully met the inclusion criteria. Closer analysis of these 8 publications revealed that they would not produce clear meta-analytical data. This made it necessary to limit the data collected to the following six items: number and type of injuries, initial therapeutic intervention, duration of follow-up, number, and type of different pulp consequences. (4) Conclusions: While orthodontic techniques are commonly used to treat dental intrusions, in the case of extrusive and lateral luxation injuries, they are less frequently used and the orthodontic approach is generally confined to the stabilization phase. Among the various possible pulp consequences, many authors consider only pulp canal obliteration (PCO) and pulp necrosis (PN), often tending to overlook physiological healing (pulp survival) and the possible development of PN after PCO. There is therefore a clear need for new, high-quality clinical studies of this topic based on systematic and standardized data collection.
2020
- Biological, genetic and aetiology aspects in molar incisor hypomineralization
[Articolo su rivista]
Apponi, R.; Presti, S.; Spinas, E.; Giannetti, L.
abstract
2020
- Combined Orthodontic and Restorative Minimally Invasive Approach to Diastema and Morphology Management in the Esthetic Area. Clinical Multidisciplinary Case Report with 3-Year Follow-Up
[Articolo su rivista]
Giannetti, L; Apponi, R
abstract
Ceramic laminates are restorations that are bonded using adhesive techniques, which provide for the treatment of the prepared dental elements according to well-defined steps. Adhesive cementation guarantees high predictability and esthetics. Orthodontic treatment is the first choice in patients with a dental misalignment. Patients who have dental element color and shape issues will undergo restorative treatment following orthodontics. Case Report. This clinical report describes a case treated with an interdisciplinary approach (orthodontic and prosthetic) of a patient who presented with diastemas, inversion of dental axes, small clinical crowns, and chromatic imperfections in the anterior maxillary teeth. The esthetic expectations of the patient for the anterior portion of the maxillary anterior teeth have been successfully achieved through orthodontic treatment and the realization of ceramic veneers. An accurate interdisciplinary evaluation of the treatment was necessary for a satisfactory result in the anterior maxillary teeth esthetically compromised in several aspects. Discussion. The modern materials used with the strict protocol of the adhesive procedures allow a minimally invasive, highly esthetic approach with an excellent long-term prognosis. The restorations must reproduce the physiological characteristics of the natural teeth aiming at an excellent biological, biomechanical, functional, and esthetic integration. Many adult patients come to visit with a combination of problems; the esthetic rehabilitation of these cases requires the evaluation of the quantity of gingival exposure, of the gingival architecture, of the size of the clinical crowns, and of the dental position. The ideal treatment of these cases involves an interdisciplinary approach. Prosthodontists, periodontists, orthodontists, and dental technicians must work together because the understanding of the various phases of treatment is fundamental to achieve the desired clinical result.
2020
- Papillon-Lefèvre syndrome: Oral aspects and treatment
[Articolo su rivista]
Giannetti, L.; Apponi, R.; Dello Diago, A. M.; Jafferany, M.; Goldust, M.; Sadoughifar, R.
abstract
Papillon-Lefèvre syndrome (PLS) is a rare disorder characterized by diffuse palmoplantar erythematous, fissured hyperkeratosis, and aggressive periodontal disease that starts in the early periods of childhood. Periodontal disease occurs with the early loss of deciduous teeth at the age of 2 to 4 years, followed by the loss of permanent teeth during adolescence. Prosthodontics management of PLS patients is very complex and sometimes requires invasive therapeutic treatments. Early diagnosis is essential for correct treatment management avoiding the possibility that patients are early edentulous. Management could be a conventional periodontal treatment and pharmacological therapy but in severe cases, digital techniques, could be help the clinician for increased patient comfort and minimized tissue damage.
2019
- Capecitabine-induced eruptive acral hyperpigmentation: Clinical and dermoscopic evaluation of two cases
[Articolo su rivista]
Peccerillo, Francesca; Pampena, Riccardo; Giannetti, Luca; Pellacani, Giovanni; Longo, Caterina
abstract
nd
2019
- DELAYED TOOTH REPLANTATION AND INFLAMMATORY ROOT RESORPTION IN CHILDHOOD AND ADOLESCENCE
[Articolo su rivista]
Spinas, E; Generali, L; Mameli, A; Demontis, C; Martinelli, D; Giannetti, L
abstract
Avulsion of one or more permanent teeth represents an emergency in dentistry. The main treatment is the replantation of the tooth/teeth as soon as possible to decrease possible complications. However, this is not always possible, and, in many cases, the patient undergoes a delayed replantation and subsequently prosthetic and implant treatments. This becomes problematic when the traumatized patient is a child; in this case, the goal is to maintain the space for the subsequent implant positioning and to give an adequate aesthetic result until the bone growth has ceased. A review on the incidence of the inflammatory root resorption onset after delayed replantation was carried out to check the frequency and severity of these complications.
2019
- Implant conometric connection through innovative prosthetic abutment: Biological, clinical, surgical, and prosthetic aspects
[Articolo su rivista]
Giannetti, L.; Spinas, Enrico.; Diago, A. Murri Dello; Consolo, U.; Generali, Luigi
abstract
The aim of this work was to describe the rehabilitation of a superior monoedentulia by positioning a conometric connection implant and a prosthetic crown using CAD/CAM technique. Surgical steps are explained and the biological aspects of this particular morse conometrical connection are evaluated, with particular attention to the possibility of removing the crown by means of an innovative attachment hole in the abutment. This type of monoedentulia can now be solved by implant-prosthetic replacement, and the dentist must choose the most suitable implant for each individual case, the most favorable connection and the most appropriate prosthetic material with regard to bone and soft tissue biology.
2019
- Lesions Mimicking Melanoma at Dermoscopy Confirmed Basal Cell Carcinoma: Evaluation with Reflectance Confocal Microscopy
[Articolo su rivista]
Peccerillo, Francesca; Mandel, Victor Desmond; DI TULLIO, Francesca; Ciardo, Silvana; Chester, Johanna; Kaleci, Shaniko; DE CARVALHO, Nathalie; DEL DUCA, Ester; Giannetti, Luca; Mazzoni, Laura; Nisticò, Steven Paul; Stanganelli, Ignazio; Pellacani, Giovanni; Farnetani, Francesca
abstract
Background: Atypical basal cell carcinoma (BCC), characterized by equivocal dermoscopic features typical of malignant melanoma (MM), can be difficult to diagnose. Reflectance confocal microscopy (RCM) enables in vivo imaging at nearly histological resolution. Objectives: To evaluate with RCM atypical melanocytic lesions identified in dermoscopy, according to common RCM criteria for the differential diagnosis of BCC, and to identify representative RCM parameters for superficial (sBCCs) and nonsuperficial (nsBCCs) basal cell carcinomas (BCCs). Methods: A retrospective analysis of consecutive patients evaluated with RCM, selecting excised lesions classified at dermoscopy with ≥1 score from the re visited 7-point checklist, mimicking melanoma, registered between 2010 and 2016. Cluster analysis identified BCC subclassifications. Results: Of 178 atypical lesions, 34 lesions were diagnosed as BCCs with RCM. Lesions were confirmed BCCs with histopathology. Dermoscopic features included atypical network (55.9%) and regression structures (35.5%) associated with sBCCs, and an atypical vascular pattern (58.8%) and irregular blotches (58.8%) with nsBCCs. Hierarchical cluster analysis identified 2 clusters: cluster 1 (100% sBCCs) was characterized by the presence of cords connected to the epidermis (90%, p < 0.001), tumor islands located in the epidermis (100%, p < 0.001), smaller vascular diameter (100%, p < 0.001) and solar elastosis (90%, p = 0.017), and cluster 2 (nsBCCs 85%) was defined by the dermic location of tumor islands (87.5%, p < 0.001) with branch-like structures (70.8%, p = 0.007) and surrounding collagen (83.3%, p = 0.012), peripheral palisading (83.3%, p = 0.012) and coiled vascular morphology (79.2%, p < 0.001) with a larger vascular diameter (50%, p < 0.001). Conclusions: RCM is able to diagnose BCCs mimicking melanoma at dermoscopy and seems able to identify sBCCs and nsBCCs.
2019
- Linear white lesion in the oral mucosa
[Articolo su rivista]
Ferreli, C.; Giannetti, L.; Robustelli Test, E.; Atzori, L.; Rongioletti, F.
abstract
Two unrelated patients aged 60 and 61 presented with an asymptomatic, white, slightly raised line on the buccal mucosa extending bilaterally from the commissure to the last molar teeth along their occlusal line, involving also the inner lower lip mucosa (Fig 1, A and B). The lesions could not wipe off on scratching. Medical history was unremarkable. Histopathology showed hyperparakeratosis without granular layers and regular acanthosis vacuolated cells in the upper spinous cell layer with some dyskeratotic cells in the absence of dysplasia (Fig 2). Neither inflammatory infiltrate nor bacterial colonies attached to the surface or fungal elements were seen (Fig 3).
2019
- Metallurgical characterization of Reciproc and Reciproc Blue Ni-Ti instruments
[Abstract in Rivista]
Generali, Luigi; Borghi, Alessia; Puddu, Pietro; Lusvarghi, Luca; Brancolini, SIMONE DOMENICO; Bertoldi, Carlo; Giannetti, Luca; Consolo, Ugo; Eugenio, Pedullà
abstract
Reciproc and Reciproc Blue files are composed of the same NiTi alloy but they undergo different thermal treatment. The Reciproc Blue show a titanium oxide superficial layer as confirmed by Raman spectroscopy and are more flexible than Reciproc M-Wire due to their different thermal treatment. The smaller and denser grains of Reciproc Blue files are responsible for the different transition temperatures of the two instruments.
2019
- Morphological classification of melanoma metastasis with reflectance confocal microscopy
[Articolo su rivista]
Farnetani, F; Manfredini, M; Longhitano, S; Chester, J; Shaniko, K; Cinotti, E; Mazzoni, L; Venturini, M; Manganoni, A; Longo, C; Reggiani-Bonetti, L; Giannetti, L; Rubegni, P; Calzavara-Pinton, P; Stanganelli, I; Perrot, J L; Pellacani, G
abstract
Cutaneous malignant melanoma metastases differential diagnosis is challenging, as clinical and dermoscopic features can simulate primary melanoma or other benign or malignant skin neoplasms, and in-vivo reflectance confocal microscopy could assist. Our aim was to identify specific reflectance confocal microscopy features for cutaneous malignant melanoma metastases, and epidermal and dermal involvement.
2019
- Orthodontic extrusion for pre-im-plant site enhancement in a posterior area: An interdisciplinary case report
[Articolo su rivista]
Giannetti, L.; Consolo, U.; Vecci, F.; Apponi, R.
abstract
Replacing a compromised dental element with a dental implant is a well documented procedure with a high success rate. The immediate placement of a dental implant at the time of extraction requires a favorable anatomical scenario. If the anatomical scenario is not ideal, it is possible to perform surgical procedures in order to increase hard and soft tissues after tooth extraction or to do orthodontic extrusion, which reduces the number of surgical procedures and times. Extrusion must be followed by a prolonged retention period to allow remodeling and adaptation of the periodontal tissues with the new tooth position. Orthodontic extrusion makes the positioning of dental implants more favorable. Ridge preservation allows placement of the dental implant within the bone thickness on a suitable axis. The case presented included orthodontic extrusion and, subsequently, the extraction of a compromised tooth in order to guarantee an ideal quantity of hard and soft tissues for positioning a post-extraction implant.
2019
- TOOTH AVULSION WITH EXTRA ORAL TIME IN LESS THAN 60 MINUTES: TWO DIFFERENT THERAPEUTIC PROTOCOLS WITH 13-YEAR FOLLOW-UP
[Articolo su rivista]
Giannetti, Luca; Spinas, Enrico; Murri dello diano, Alberto
abstract
The aim of this study is to assess what needs to be the priority in tooth avulsion: replantation as quickly as possible and deferred endodontic treatment, or replantation and elimination of every irritating stimulus for the periodontal ligament. Twenty patients were selected and divided into 2 groups: in group A attention was focused on the rapidity of replantation and postponed endodontic therapy, in group B we focused on the elimination of the necrotic pulp with extraoral endodontic therapy. Clinically, there was no difference in stability, but there were 3 elements in infraocclusion in group A, and 4 in group B. Radiographically, a similar incidence of radicular resorption caould be observed in group B compared to group A. In conclusion, as a result of dental avulsion, the speed of replanting always seems to be a priority.
2019
- The comparison of the proteomic profile of periodontal pocket and of corresponding gingival crevicular fluid to study periodontal disease biomarkers: feasibility study. biomarkers: feasibility study
[Abstract in Rivista]
Bertoldi, Carlo; Franceschetti, Filippo; Bergamini, Stefania; Giannetti, Luca; Generali, Luigi; Bellini, Pierantonio; Consolo, Ugo
abstract
Aim: Periodontitis is a set of inflammatory disorders characterized by periodontal attachment loss by periodontal pocket development, leading to tooth loss if remain untreated. The etiology and progress of periodontal disease is complex and remains mostly unknown. So, periodontal disease therapy has considerable limitations. The easy, reliable and correct early detection and control of the disease, markedly reduces biological and social costs. However, the diagnosis of periodontitis is established exclusively by clinical criteria based on probing to assess periodontal pockets, which are the pathognomonic expression of periodontal disease. The -omic sciences acquired substantial significance of late years and, in particular, proteomic seemed to be the more promising in this initial stage. Most proteomic analysis regarding periodontal diseases have been performed on saliva, crevicular fluid samples, peripheral blood or periodontal plaque samples which are more easily to harvest than the tissue of the periodontal pocket. However, they failed to provide reliable results for clinical applications. On the contrary, very few studies were directly performed on the periodontal pocket.
So, the aim of this study was to compare the proteomic profile of interproximal pocket tissues with that of GCF, and to analyze if they show a significant similarity in the proteomic profile.
Methods: in this preliminary study, we enrolled 3 healthy subjects affected by severe periodontitis needing of periodontal surgery. Immediately before the surgery, GCF samples were taken by means of filter paper strips positioned in the gingival sulcus correspondent to periodontal pockets. Then, periodontal pocket tissue, harvested during surgery, was adequately stored for proteomic analyses. All samples were immediately frozen at –80°C and maintained until further analysis. Tissue samples were mechanically disrupted and incubated in lysis buffer, while GCF was obtained incubating the collecting paper in phosphate buffered. In both cases, after centrifugation, the supernatant was precipitated in cold acetone overnight and protein content were pelleted by centrifugation and then dissolved in a rehydration buffer. Mono-dimensional gel electrophoresis was used to separate protein content. After staining gel images were acquired and compared. Liquid chromatography coupled to mass spectrometry (LC-MS/MS) analysis was performed to allow protein spot identification.
Results: 1-DE gels from periodontal pocket tissue and the correspondent GCF was analyzed by software Quantity One. Almost the same qualitative protein expression profile in pocket tissue and GCF was found from each patient. However, no statistical significant correlation between the quantitative proteomic profile of pocket tissue and GCF was found. Only one band (that of K immunoglobulin) resulted statistically significant between GCF and pocket tissue proteome in all patients.
Conclusions To date, this is the first study comparing the proteome of periodontal pocket tissue and corresponding GCF. The periodontal pocket and the GCF are similar as proteomic networks, but the protein network of the periodontal pocket does not influence significantly the GCF protein network and the other way around. So, with the limitations of this study, the preliminary results seem to indicate that the GCF does not seem suitable to study on the pathogenesis of periodontal disease explaining the reason for the failure of studies based only on GCF to control the periodontal disease in real-time.
2019
- The use of only enamel matrix derivative allows outstanding regeneration results in periodontal intrabony defect treatment: a retrospective study
[Articolo su rivista]
Bertoldi, C.; Ferrari, M.; Giannetti, L.
abstract
Periodontal tissue regeneration depends on several biological, homeostatic and regulative variables that directly induce the clinical features. The aim of this study is to compare the clinical results obtained using the enamel matrix derivative peptide (EMP) compared to the less manageable association of EMP and bovine bone xenographic (BPBM) in the treatment of deep intraosseous defects. Ten healthy patients, suffering from moderate or severe chronic periodontitis, having at least two deep and narrow intrabony defects in the same dental arch and needing surgical treatment, were selected. The same patient was treated with the two different materials: EMP -TG1 in one defect and the association-TG2 in the other. Immediately before surgery (T0) and 12-month after (T2) the probing depth (PD) and gingival recession (GR) were registered at the experimental sites. No statistically significant differences were shown between TG1 and TG2 at T0 nor at T1 in term of PD and GR, while a statistically significant PD decrease was found both in TG1 and TG2 between T0 and T1 (p less than 0.05). GR increase resulted statistically significant in TG1 (p less than 0.05) but not in TG2 between T0 and T1 (p≥0.05). In this split-mouth retrospective study, both the treatments achieve favourable clinical results but the TG1 shows a significant increase in GR probably because EMP is not able to support the gingiva covering the intrabony defect. Therefore, the choice of the type of periodontal defect to be treated with EMP will be a therapeutic key-point.
2018
- Behcet's disease: Minireview with emphasis on oral aspects
[Articolo su rivista]
Giannetti, Luca; Murri Dello Diago, Alberto; Lo Muzio, Lorenzo
abstract
Adamatiades-Beli9et disease (B D) is a primary systemic vasculitis of unknown origin, that may involve blood vessels of all sizes. The clinical hall-mark of the disease are recurrent oral aphthous ulcers, painful, sharply margined and often associated with recurrent genital ulcers. A variety of skin lesions, such as erythema nodosum-like nodules and purpuric lesions are frequently observed. Less common manifestations of B D include thrombophlebitis, central nervous system and ocular inflammation which, however, may impact significant morbidity and mortality. The etiology is unknown, although genetic factors, infectious agents, oral and salivary microbioma, and immunologic mechanisms are implicated and studied. Topical and eventually systemic corticosteroids are the choice treatment.
2018
- Deep infiltration for the treatment of hypomineralized enamel lesions in a patient with molar incisor hypomineralization: A clinical case
[Articolo su rivista]
Giannetti, L.; Murri Dello Diago, A.; Corciolani, E.; Spinas, E.
abstract
This case report presents the technique of deep infiltration for the treatment of hypomineralized enamel lesions in a patient affected by molar incisor hypomineralization (MIH) with the purpose of obtaining an aesthetic improvement in the affected vestibular enamel. Deep infiltration treatment involves a sequence of steps starting with an initial mechanical abrasion of the outside surface of the enamel, followed by a phase of chemical erosion using 15% hydrochloric acid, penetration through the porosity of the enamel by a very fluid resin, and finally the repair of the thin layer of lost enamel using a composite. The aesthetic improvement of the elements affected by hypomineralized lesions is discernable immediately following treatment and becomes more accentuated with time. At the expense of minimal damage to surface enamel, deep infiltration enables treatment of all types of white spot enamel lesions, regardless of aetiology, offering the possibility of restoring an aesthetically pleasing smile for patients.
2018
- Dental injuries in young athletes, a five-year follow-up study
[Articolo su rivista]
Spinas, E.; Giannetti, L.; Mameli, A.; Re, D.
abstract
Aim The aim of this study is to produce a clinical therapy protocol for a group of 20 athletes between the ages of 8 and 14, who all suffered traumas affecting hard dental and periodontal tissues. Material and methods This study involves a group of 20 athletes (10 male and 10 female) who had suffered dental traumas of varying severity. In order to collect the data, two classification systems were used: one for hard tissue traumas and another for periodontal lesions. The athletes were subdivided into lesion groups, treated depending on the type of lesions and then followed-up over a period of 5 years. A statistical analysis was carried out to study the association between type of lesions, types of sports and the number of teeth involved. Results We found that recovery time ranged from 3 to 5 days for uncomplicated fractures and up to 14 days for luxations. Only four complications were registered during the follow-up period and these were most likely due to the severity of the trauma. Out of the 20 athletes, 16 had begun and maintained the habit of using mouth protection devices when practicing their sport. The statistical analysis focused on the possible association between the risk levels of a sport and the typical lesions and complications that usually occur. Due to their high frequency, the two types of lesions taken into account in our study were complicated fractures (FP) and luxated/fractured teeth (LF). The average number of teeth involved varied according to the sport's risk level (medium or high) with averages of 1.6 teeth involved for medium-risk sports and 2.0 teeth for high-risk sports. Conclusions What emerged in particular was the regular progress in the recovery time needed for the injuries sustained, with few complications or delays in rehabilitation; we also noted that the numerous athletes who habitually used mouthguards while competing during the recovery period did not suffer any recurrences of injuries or further complications. Regarding the results of our statistical analysis, no association was found between the sport's risk, the types of lesions and the occurrence of complications. In addition, analysis of the average number of teeth involved showed that there is no statistical evidence to reject the hypothesis that the ratios remain the same in the two groups.
2018
- Effect of Self-Adjusting file and WaveOne reciprocating file on the filling ability of oval-shaped canals with thermoplasticized gutta-percha
[Articolo su rivista]
Generali, L; Cavani, F; Righi, E; Murri Dello Diago, A; Spinas, E; Giannetti, L
abstract
The aim of the study was to compare the effect of Self-Adjusting Files (SAF) and WaveOne Primary file with syringe and needle irrigation on the filling ability of oval-shaped root canals obturated with thermoplasticized gutta-percha. Twenty-four single root teeth with single oval-shaped root canals were distributed in two experimental homogeneous group. One group was instrumented and cleansed using the SAF system while in the other group the WaveOne system with syringe and needle irrigation was used. After instrumentation, the roots were filled by Thermafil Obturators and TopSeal sealer. Specimens were transversally sectioned at 2-, 5- and 7-mm levels from the apex and observed under light microscope. The percentage of gutta-percha filled area (PGFA), the percentage of sealer filled area (PSFA) and the percentage of voids area (PVA) were measured for each section, moreover the percentage of completely filled sections was evaluated. At all levels, no significant differences in terms of PGFA, PSFA, PVA and percentage of completely filled canals between groups were obtained (P > .05). On the contrary, when the data were pooled, the mean PGFA in the SAF group was 95.8%, whereas it was 93.2% in the WaveOne group (P < 0.05). The percentage of sections completely filled was 77.8% in the SAF group, while 52.8% in the WaveOne group (P < 0.05). Overall, the use of the SAF system in oval canals allows to obtain a significantly greater complete filling than the use of the WaveOne system.
2018
- MIH: indagine conoscitiva tra gli odontoiatri nelle province di Modena e Reggio Emilia
[Articolo su rivista]
Giannetti, L; Bartoli, G; Banchelli, F; Spinas, E; Murri dello Diago, A
abstract
Lo studio vuole: indagare percezione, esperienza e scelte terapeutiche degli odontoiatri che operano nelle province di Modena e Reggio Emilia riguardo alla sindrome MIH; valutare eventuali differenze nelle risposte tra pedodonzisti e dentisti generici e tra i lavoratori in base agli anni di attività.
2018
- Oral lichen planus
[Articolo su rivista]
Giannetti, Luca; MURRI DELLO DIAGO, Alberto; Spinas, Enrico
abstract
Oral Lichen Planus (OLP) is the most frequent mucosal localization of Lichen Planus, affecting about 1-2% of the population. It is associated with skin lesions in 60-70% of cases, while occurring as the only manifestations in 15-25% of patients. Six clinical forms of OLP are identified: reticular (the most common), plaque, papular, atrophic, vesicles-bullous and erosive. The evolution is chronic, especially in the erosive form. A 1% incidence of squamous-cell carcinoma has been reported, thus considering OLP a potential premalignant condition. The etiopathogenesis is still not completely understood: genetic (HLA-DR2), immunologic (T cell-mediated) and infectious (association with viral hepatitis C, differences in oral microbiota in OLP, and bacteria internalization into infiltrating T cells and oral epithelial cells) are considered the main predisposing or provoking factors. Management is based on the severity of the lesions; topical steroids are the first-line therapy and oral glucocorticoids are used for severe erosive lesions.
2018
- Oral pemphigus
[Articolo su rivista]
Giannetti, Luca; Generali, Luigi; Bertoldi, Carlo
abstract
The involvement of the oral mucosa in patients affected by pemphigus vulgaris (PV), paraneoplastic, IgA pemphigus, and in some cases iatrogenic pemphigus is common and often a prelude to skin lesions. Intraepidermal bullae are caused by acantholysis, induced by IgG autoantibodies directed against the desmosomes and the domain of numerous keratinocytes self-antigens desmogleins (namely cadherins), thus supporting the autoimmune nature of the disease. Apoptosis may contribute to the acantholysis. Oral mucosal lesions are more commonly refractory to treatment compared to skin lesions and have been associated with disease duration, disease location and possibly the presence of HSV DNA in the oral cavity. Recent publications have stressed the positive role of Rituximab in early disease treatment.
2018
- Recurrent aphtous stomatitis
[Articolo su rivista]
Giannetti, Luca; MURRI DELLO DIAGO, Alberto; Lo Muzio, Lorenzo
abstract
Recurrent aphtous stomatitis is the most common ulcerative disease of the oral mucosa. In this paper we presented the main clinical
2018
- Resurfacing with Ablation of Periorbital Skin Technique: Indications, Efficacy, Safety, and 3D Assessment from a Pilot Study.
[Articolo su rivista]
Guida, S; Nisticò, Sp; Farnetani, F; Del Duca, E; De Carvalho, N; Persechino, F; Verdina, T; Giannetti, L; D'Alessandro, M; Urtis, Gg; Pellacani, G; D'Alessandro, G.
abstract
OBJECTIVES AND BACKGROUND:
Nowadays, several approaches for skin rejuvenation of the lower eyelid are available. We present a new technique of resurfacing with ablation of periorbital skin (RAP) performed in a single session.
METHODS:
This is a retrospective study involving 20 patients showing skin elastosis with or without evidence of the nasojugal fold and atrophic and dyschromic skin or needing a combined approach of transconjuntival lower blepharoplasty for fat bag removal. RAP technique is assessed in terms of efficacy, safety, and 3D evaluation of results at 6 months' follow-up.
RESULTS:
Global Assessment Improvement Scale results highlighted an improvement in all cases, for both physicians (blinded to treatment) and individual subjects. Only minor adverse events (edema, erythema, and discoloration) were reported in almost all patients, lasting 2-3 weeks after treatment, and were resolved without intervention. A 3D imaging tool revealed the reduction of medium protrusions and depressions and an improved texture at 2 months. Skin recovery was inversely correlated with hemoglobin reduction.
CONCLUSIONS:
RAP seems to offer expert dermatologists a safe and clinically effective technique for skin rejuvenation of lower eyelids, without significant adverse events. Further studies will be performed to confirm our results.
2018
- SDR® vs traditional composite in class II restorations in primary molars
[Articolo su rivista]
Giannetti, L.; Murri Dello Diago, A.; Spinas, E.
abstract
This study aims to compare the clinical characteristics of a new flowable resin-based composite with those of a traditional composite when applied to deciduous molars for class II restorations. Twenty-eight children between 6-12 years of age, with paired minimal Class II cavities present on their primary molars, were chosen. The paired cavities were restored with either a microhybrid composite or a new flowable resin-based composite. The composites were assigned to cavities in either the right or left side of the mouth, using random allocation tables. Each pair of restorations were clinically assessed at six-month intervals following the United States Public Health Service criteria. The prevalence of carious lesions was higher in maxillar molars (53.6%) compared to the mandibular molars (46.4%). At 24 months, Charlie or Delta scores in the paired groups were not seen in any patient, thus demonstrating a clinical success. The statistical analysis using Pearson's chi-squared test did not reveal significant p-values for any parameter except the proximal contact showing significant p-values for this parameter. SDR appears to be the material of choice for the restoration of deciduous teeth due to its clinical features shown at 24 months as well as its ease and speed of application.
2018
- SUPERFICIAL INFILTRATION TO TREAT WHITE HYPOMINERALIZED DEFECTS OF ENAMEL: CLINICAL TRIAL WITH 12-MONTH FOLLOW-UP
[Articolo su rivista]
Giannetti, L; Dello Diago, Am; Silingardi, Giulia; Spinas, E
abstract
Hypomineralization represents one of the most common defects in tooth crowns. Thanks to a wide understanding of aesthetics, patients request a treatment to resolve these defects. Different techniques are available, such as crowns/veneers, traditional restorative treatments, microabrasion, whitening, remineralizing agents and infiltration technique. The objective of this trial is to assess the effectiveness of superficial infiltration with Icon (DMG, Hamburg, Germany) on the attenuation of crown hypomineralized lesions of various etiological origins with a 12-month follow-up. Seventeen patients with white defects of enamel in the aesthetic sector were selected. The infiltration procedure was carried out following the manufacturer's instructions. Intraoral photographs were taken before and directly after treatment in order to document the immediate change in colour. Check-ups were performed 1 and 12 months later. All the defects which were treated showed a degree of attenuation. The teeth affected by molar incisor hypomineralization (MIH) showed partial attenuation in 8 cases, and only in one case the defect disappeared. Regarding the post-trauma cases, 6 were partially attenuated and 2 disappeared. The post orthodontic defects disappeared in 6 cases and were attenuated in 5. All incipient caries defects were completely hidden. Four out of 6 cases of fluorosis disappeared. Diagnosis plays a key role in guiding the dental clinical selection of treatment. While it has always been possible to achieve a high level of attenuation in cases of fluorosis and lesions of caries origin, cases of MIH should probably be treated using more invasive techniques. Post-trauma lesions should be infiltrated with caution, and only after having informed the patient of the possible ineffective outcome.
2018
- Traumatic dental injuries resulting from sports activities; immediate treatment and five years follow-up: An observational study
[Articolo su rivista]
Spinas, Enrico; Mameli, Antonello; Giannetti, Luca
abstract
Background: Traumatic dental injuries (TDIs) represent 18-30% of all oral pathologies and a considerable number of these are sports related. It is very important to treat sports-related injuries and prevent complications. However, very few studies investigate the most expedient therapeutic strategies for the treatment of dental trauma correlated to sports. Objective: The aim of this work was to focus on the average recovery time for different lesions, to assess adequate times for each athlete, to identify any association with complications and to investigate whether or not the use of mouth-guards interfered with a full recovery to normal health. Methods: This study involved a group of 30 athletes (15 male and 15 female) who had dental injuries of varying severity. For the purposes of data collection, two classifications were taken into account: a classification for hard tissue trauma and another for periodontal lesions. The athletes were subdivided in “type of lesion’ groups”.They were then treated depending on their individual lesions and followed up for 5 years. A statistical analysis was carried out to study the association between recovery time, lesion types and occurrence of complications. Results: The time for recovery was different for each type of lesion and ranged from 3-5 days (only uncomplicated fractures) to 14 days (all hard-periodontal tissue traumas). The total number of recorded pulp complications amounted to 6 cases. Among 30 athletes, 20 had begun and maintained, during the five-year follow-up period, the habit of using mouth-guards when practicing their sport activities. Conclusions: Recovery time and the severity of lesions are statistically associated: the more serious the injury, the more time an athlete needs to recover and return to competitive sports events. Furthermore, recovery time and precautionary measures (mouth-guards) did not influence the onset of complications. The subjects’ habit of wearing a mouth guard continued even after the end of the therapy and follow-up periods.
2017
- Single tooth anaesthesia: A new approach to the paediatric patient. A clinical experimental study
[Articolo su rivista]
Giannetti, L.; Forabosco, E.; Spinas, E.; Re, D.; Murri Dello Diago, A.
abstract
Aim The objective of this study is to assess the efficacy of the STA Wand System with respect to pain and fear reduction in paediatric patients and by using the Single Tooth Anaesthesia (STA) technique. Methods Patients included children and teenagers between 6 and 17 years of age, who required the administration of local anaesthesia prior to expected treatments. Local anaesthesia was performed by means of the electronic STA Wand System (Milestone scientific., Inc.) adopting the Single Tooth Anaesthesia (STA) technique. Pre- and post-anaesthesia, the patients were asked to complete the Wong-Baker faces image scale and the provider filled in the Frankl Scale. Results All treatments were completed successfully and no collaboration issues were recorded. Frankl's assessment showed that 91% of patients regarded dental experience positively. The efficacy of the computer-assisted anaesthesia was at 100% when treating primary teeth, and 70% for procedures on permanent teeth. Almost the totality of treated patients (94%) gave a positive evaluation after having tried the device with STA technique. Only 6% of the patients assessed the procedure negatively. Conclusions The STA technique allows for absence of anticipatory anxiety, absence of physical pain, no anaesthetic effects in the perioral tissues and a controllable, lower dosage of the anaesthetic liquid.
2015
- Fordyce granules and hyperplastic mucosal sebaceous glands as distinctive stigmata in Muir-Torre syndrome patients: characterization with reflectance confocal microscopy
[Articolo su rivista]
Ponti, Giovanni; Meschieri, Andrea; Pollio, Annamaria; Ruini, Cristel; Manfredini, Marco; Longo, Caterina; Mandel, Victor Desmond; Ciardo, Silvana; Tomasi, Aldo; Giannetti, Luca; Pellacani, Giovanni
abstract
Background: The Muir-Torre syndrome (MTS), a variant of Lynch syndrome (LS), is characterized by the presence of sebaceous skin adenomas and/or carcinomas and keratoacanthomas associated with visceral malignancies. Fordyce granules (FGs) are oral mucosal lesions previously found in association with LS. The aim of this study was to analyze the specific frequency of FGs in sporadic individuals and gene carriers patients with MTS of known mismatch repair genes mutations. The secondary aim was to characterize FGs by means of reflectance confocal microscopy (RCM). Methods: A total of 13 patients belonging to nine different genetically unrelated MTS kindreds (MLH1 gene mutation n = 2; MSH2 gene mutation n = 11) and 140 genetically unrelated healthy controls were examined. Depending on the clinical examination of the oral mucosa surface, subjects were categorized as either FGs positive or FGs negative. Results: FGs were diagnosed in 13 of 13 (100%) of MMR gene carriers patients with MTS vs. 9 of 140 (6.4%) controls. The most common site for FGs in MTS was the vestibular oral mucosa, compared with the gingival mandibular and retromandibular pad in controls. RCM examination found multiple sebaceous acinar cells that appear as round or oval hyper-refractive globules and that create a lobular aspects of the sebaceous glands defined as 'moruliform' or 'berry-like' structures. Conclusions: Clinical and RCM evidences of our study suggest that an activation of the sebaceous glands system occurs in patients with MTS. Fordyce granules and intra-oral sebaceous hyperplasia may constitute an additional clinical parameter, which may be adopted to distinguish individuals with highest likelihood of being affected from MTS.
2015
- Preventive treatment of post-traumatic dental infraocclusion: study on the knowledge of dental decoronation in a sample of Italian dental students and dentists
[Articolo su rivista]
Spinas, E.; Aresu, M.; Canargiu, F.; Giannetti, L.
abstract
AIM: The aim of the present work is to investigate whether dental decoronation is a procedure known by a sample of dental students and Italian dentists. Dental decoronation technique is performed in order to mitigate the outcomes which may occur after a delayed tooth replantation.MATERIALS AND METHODS: A cognitive survey about the knowledge of the dental decoronation technique was carried on two groups: a sample of 120 dental students (5th year of dental school), from University of Cagliari, Sassari and of Chieti-Pescara (60 males and 60 females), and a group which involved 200 Italian dentists (age comprised between 25 and 45, 130 females and 70 males) enrolled at pedodontics and orthodontics Masters and CE courses (University of Roma Sapienza, Chieti- Pescara, Cagliari). The latter group's main field of work was paediatric dentistry and orthodontics, two dental specialties often involved in treating Traumatic dental injuries.RESULTS: Only 20 dentists out of the 200 interviewed answered that they knew this technique and only 5 of them proved to know it and were able to describe it correctly. No students interviewed knew this technique.CONCLUSION: It is apparent from the results of this survey that there is very little information about the dental decoronation technique both during the Degree Course in Dentistry and Post Graduate specialty programmes (Continuing Education Courses and Masters).
2014
- A confocal microscopic evaluation of dentinal tubule penetration and percentage of root canal sealer using three different instrumentation techniques
[Abstract in Rivista]
Generali, Luigi; Pettenati, C.; Gandolfi, M. G.; Righi, Elena; Franchi, I.; Bertoldi, Carlo; Giannetti, Luca; Consolo, Ugo
abstract
Vedasi l'allegato
2014
- Filling ability of carrier-based obturation system in oval-shaped canals prepared with reciprocating and adaptative instruments.
[Abstract in Rivista]
Generali, Luigi; L., Pastorello; M. G., Gandolfi; Righi, Elena; Giannetti, Luca; Bertoldi, Carlo; C., Prati
abstract
Vedi Allegato
2014
- Foreign body mimicking an oral pathology
[Abstract in Rivista]
Bellini, Pierantonio; Salgarelli, Attilio Carlo; Bertoldi, Carlo; Generali, Luigi; Giannetti, Luca; Consolo, Ugo
abstract
vedasi l'allegato
2014
- Implant surface alterations following the use of three instrumentation systems: 1 - effects of a standard cleaning
[Abstract in Rivista]
Bertoldi, Carlo; Battarra, F.; Lusuardi, D.; Giannetti, Luca; Generali, Luigi; Consolo, Ugo; Zaffe, Davide
abstract
Vedasi l'allegato
2014
- Implant surface alterations following the use of three instrumentation systems: 2 - simulation of an extended treatment
[Abstract in Rivista]
Bertoldi, Carlo; Ventura, S.; Lusuardi, D.; Sassatelli, Paolo; Generali, Luigi; Giannetti, Luca; Consolo, Ugo; Zaffe, Davide
abstract
Vedasi l'allegato
2014
- Open and closed sandwich technique in class II restorations. Evaluation of marginal integrity bi SEM analysis.
[Abstract in Rivista]
Giannetti, Luca; E., Gelati; E., Spinas; Generali, Luigi; Bertoldi, Carlo; A. B., Murri Dello Diago
abstract
Vedi allegato
2014
- The peripheral seal concept in adhesive dentistry: A clinical application.
[Abstract in Rivista]
Giannetti, Luca; A., Bassoli; Generali, Luigi; E., Spinas; Bertoldi, Carlo; A., Murri Dello Diago
abstract
Vedi allegato
2014
- Use of mouth guard in basketball: observational study of a group of teenagers with and without motivational reinforcement
[Articolo su rivista]
Spinas, E.; Aresu, M.; Giannetti, L.
abstract
AIM: This study aims at ascertaining the capacity of 2 groups of young athletes to be faithful to the initial oral prevention project, with the difference that the study group received motivational reminders by either researchers and technical staff members of the team during the observation period, while the control group did not receive any motivational reminders.MATERIALS AND METHODS: This observational study was based on two groups selected from a wide group of 150 adolescent basketball players who accepted to use a custom-made mouth guard during their sport sessions. None of the selected athletes (60 adolescents aged between 12 and 15 years) had ever worn a mouth guard during their sports activity. A customised mouth guard was supplied, and subjetcs were requested to wear it for 12 months during training sessions and competitions. The study group was composed of 30 athletes, 15 males and 15 females, who received a constant motivational reinforcement to the use of the mouth guard by their coach and during checkups. Similarly, the control group was composed of 30 athletes (15 males and 15 females) who did not receive any motivational reinforcement.RESULTS: Twelve months after the beginning of the study, 24 subjects belonging to the control group were not using the mouth guard, while only 7 subjects of the study group were not using it. It was also noticed, six months after the beginning of the observation period, a rapid decline in the participants' interest in the use of the mouth guard.CONCLUSION: No traumatic event was registered among those adolescents who had used the mouth guard for the whole period of the study. Female athletes showed greater compliance to this prevention project. It is important that all technical staff members, and particularly the leading coach, encourage the regular use of oral protection devices for prevention among teenagers practicing sports.
2012
- A RANDOMIZED LONGITUDINAL STUDY ON CORONALLY ADVANCED FLAP PLUS CONNECTIVE TISSUE GRAFT IN THE TREATMENT OF MULTIPLE GINGIVAL RECESSIONS: A PILOT STUDY.
[Abstract in Atti di Convegno]
Melpignano, F.; Simonazzi, L.; Lucchi, A.; Giannetti, Luca; Consolo, Ugo; Bertoldi, Carlo
abstract
Vedi allegato
2012
- ALLOGRAFTS AND AUTOGRAFTS IN PARTIALLY EDENTULOUS MANDIBLES: HISTOLOGICAL DIFFERENCES AND CLINICAL AND RADIOGRAPHIC CONSIDERATIONS AT TWO YEARS FOLLOW-UP
[Abstract in Atti di Convegno]
Dotti, A.; Travaglini, Domenico; Giannetti, Luca; Bertoldi, Carlo; Consolo, Ugo
abstract
Vedi allegato
2012
- CLINICAL-RADIOGRAPHIC FOLLOW-UP OF IMPLANTS PLACED IN RECONSTRUCTED MAXILLA USING ONLAY AND/ OR INLAY THECNIQUE
[Abstract in Atti di Convegno]
Dotti, A.; Bandieri, A.; Giannetti, Luca; Bertoldi, Carlo; Bellini, Pierantonio; Travaglini, Domenico; Consolo, Ugo
abstract
Vedi allegato
2012
- Eighteen months SDR clinical performance in class II cavities. Valutazione delle performance di SDR nei restauri di classe II a 18 mesi.
[Relazione in Atti di Convegno]
Lucchi, A.; Pellacani, C.; Generali, Luigi; Bertoldi, Carlo; Giannetti, Luca
abstract
Vedi allegato
2012
- Mini implant rehabilitation in growing patient following traumatic avulsion
[Abstract in Atti di Convegno]
MURRI DELLO DIAGO, Alberto; Bertoldi, Carlo; Generali, Luigi; Consolo, Ugo; Giannetti, Luca
abstract
Vedi allegato
2012
- Replantation of immature permanent central incisors following traumatic avulsion: pulp revascularization.
[Abstract in Atti di Convegno]
MURRI DELLO DIAGO, Alberto; Bertoldi, Carlo; Generali, Luigi; Consolo, Ugo; Giannetti, Luca
abstract
Vedi allegato
2012
- VARIATION OF PERIODONTAL INDEXES DURING THE SAME DAY.
[Abstract in Atti di Convegno]
Nechytaylo, A.; Melpignano, F.; Lalla, Michele; Forabosco, Andrea; Giannetti, Luca; Consolo, Ugo; Bertoldi, Carlo
abstract
Vedi allegato
2011
- A RCT on paediatric patients: a new flowable resin-based composite vs traditional composite.
[Abstract in Rivista]
MURRI DELLO DIAGO, Alberto; Generali, Luigi; Lucchi, A.; Bertoldi, Carlo; Consolo, Ugo; Giannetti, Luca
abstract
Vedi allegato
2011
- A new flowable resin-based composite clinical performance in Class II cavities: a split-mouth study.
[Abstract in Rivista]
Guaitolini, S.; Bertoldi, Carlo; Giannetti, Luca; MURRI DELLO DIAGO, Alberto; Generali, Luigi; Consolo, Ugo
abstract
Vedi allegato
2011
- Coronally advanced flap versus connective tissue graft in the treatment of single gingival recessions: a randomized study.
[Abstract in Rivista]
Pellacani, C.; Giannetti, Luca; Lucchi, A.; Guaitolini, S.; Murri Dello Diago, A.; Consolo, Ugo; Bertoldi, Carlo
abstract
Vedi allegato
2011
- Direct composite reconstruction of fractured teeth: case report.
[Abstract in Rivista]
Mancuso, R.; Franchi, I.; Bertoldi, Carlo; Giannetti, Luca; Murri Dello Diago, A.; Dotti, A.; Consolo, Ugo; Generali, Luigi
abstract
Vedi allegato
2011
- Do periodontal indexes change during the day? A cross-sectional study.
[Abstract in Rivista]
Caprara, G.; Forabosco, Andrea; Giannetti, Luca; Pellacani, C.; Guaitolini, S.; Consolo, Ugo; Bertoldi, Carlo
abstract
Vedi allegato
2011
- Is the subepithelial connective tissue graft technique more predictive than coronally advanced flap in the treatment of multiple gingival recessions? A randomized study.
[Abstract in Rivista]
Guaitolini, S.; Giannetti, Luca; Generali, Luigi; Pellacani, C.; Dotti, A.; Consolo, Ugo; Bertoldi, Carlo
abstract
Vedi allegato
2011
- Marginal integrity evaluation of class II composite restoration: a sem analysis.
[Abstract in Rivista]
Generali, Luigi; Bertoldi, Carlo; Giannetti, Luca; Murri Dello Diago, A.; Lucchi, A.; Pellacani, C.; Franchi, I.; Mancuso, R.
abstract
Vedi allegato
2011
- SDR versus traditional composite. A RCT onpaediatric patients
[Abstract in Rivista]
Giannetti, Luca; A., Murri; D., Diago
abstract
Background: There is insufficient evidence from the dental literatureto make any recommendations about which filling material touse in paediatric dentistry. Choices in these areas are made onclinical preference.Aim: The aim of this study is to evaluate the clinical behaviour ofaesthetic restorations in Class II preparations in primary molars byusing two different materials.Design: The authors conducted a randomized clinical trial. Twentyeightpatients received 56 restorations in primary molars randomlyassigned by lottery method in a split mouth technique: 28restorations with traditional universal microfilled composite and28 restorations with SDRTM (Dentsply). Two examiners, whosetechnique has been calibrated, evaluated the restorations usingmodified U.S. Public Health Service criteria at baseline and at 3,6, 9 and 12 months.Results: After 1 year, there were no statistical differences betweenSDR and traditional composite about Marginal Adaptation,Anatomical Form, Cavosurface Margin, Discoloration, AxialContour, Secondary Caries and Visible Plaque Index. However,there was a decreasing odd radio and a P < 0.05 between the twomaterials regarding the Proximal Contact.Conclusions: At the 12-month clinical recall, the authors found nodifferences among SDR and traditional composite in Class IIrestorations in primary molars. SDR showed a good behaviour andit was very appreciated by the patients and by the authors for itsfast and easy manipulation.
2011
- Tooth avulsion. A RCT on replantation of teeth withextra-oral dry time >60 minutes
[Abstract in Rivista]
A., MURRI DELLO DIAGO; Giannetti, Luca
abstract
Background: A widespread lack of knowledge about the immediatemanagement of tooth avulsion results in an extended extra oral drytime, which leads to an increase of complications.Aim: This study aims to assess what should be the endodonticapproach in the case of replantation with extraoral dry-time>60 min.Design: Thirty nine patients were selected, in the period January2004–December 2010, that had a dental element with extra-oraltime >60 min but less than 24 h. Randomization was performedso as to divide the population into two groups. Group 1, extra-oralendodontic therapy and subsequent replantation. Group 2, replantationand subsequent endodontic therapy in 7–15 days. Clinicaland radiographic evaluations were carried out.Results: All 36 patients showed a similar trend between the twogroups; at the time of splint removal clinically a reduced mobilitywas observed which was physiological after one month. Radiographicallythe trend was more variable, initially because there wasan increase in resorption processes dependent on the group. After 2and at 4 years, the resorption was similar for both groups.Conclusions: Extraoral endodontic therapy initially appeared toimprove the results, but at 4 years this tend to equalize with theother group. These data allow us to conclude that both proceduresresult in by root resorption, but both still allow the retention of theelement in the dental arch, thus preserving the space and the softand bonnie tissue.
2010
- Autotransplanted premolars replacing maxillary incisors: Esthetic outcome.
[Relazione in Atti di Convegno]
MURRI DELLO DIAGO, Alberto; Lucchi, A.; Generali, Luigi; Bertoldi, Carlo; Giannetti, Luca
abstract
RIASSUNTO
Ragioni
L’autotrapiato è sicuramente una scelta biologicamente ottimale e di sicure possibilità prognostiche. Lo scopo del presente studio è quello di valutare sia dal punto di vista del clinico che da quello del paziente il valore estetico dell’elemento auto trapiantato.
Materiali e Metodi
Sono stati selezionati 25 pazienti che in seguito a trauma abbiano eseguito l’autotrapianto di un premolare in regione mascellare superiore e che abbiano eseguito un reshaping della morfologia incisale con restauro diretto o indiretto in composito. Viene eseguita una valutazione professionale associata ad un questionario compilato dai pazienti stessi allo scopo di poter quantificare il valore estetico raggiunto.
Risultati
64 % degli elementi osservati viene valutato sovrapponibile nell’analisi professionale a fronte di un 68% di pazienti pienamente soddisfatti. Il 16 % viene valutato discordante, e due pazienti si dicono insoddisfatti.
Conclusioni
L’autotrapianto è un’opzione terapeutica di prima scelta nella riabilitazione del trauma dento-alveolare. Essa è una metodica complessa e ricca di variabili che rappresenta però vantaggi biologici unici.
Dal punto di vista estetico essa è parzialmente carente rispetto ad altre opzioni, ma se affrontata in maniera multidisciplinare permette di raggiungere ugualmente il successo a breve e lungo termine.
ABSTRACT
Background
Autotransplantation of teeth appears to be the most biologic approach. The aim of this study is to evaluate the esthetic outcome of the auto transplanted element.
Methods and Materials
25 patients have been selected after dental trauma and autotransplantation of a premolar in the maxillary region by a reshaping of the coronal morphology with direct or indirect composite restoration. It has been performed a professional assessment associated with a questionnaire filled in by patients themselves in order to be able to quantify the aesthetic outcome.
Results
64% of observed elements have been evaluated as match in the professional evaluation against a 68% of patients fully satisfied. The 16% is categorizes as mismatch, and two patients reported dissatisfaction.
Conclusions
Autotransplantation is an optimal therapeutic option after dental-alveolar trauma. It is a complex technique with unique biological advantage.
From the aesthetic point of view it is partially lacking in comparison to other options, but if approached in a multidisciplinary approach it can also achieve success in the short and long term.
2010
- Correlazione fra amalgama dentale e patologie sistemiche: analisi della letteratura.
[Relazione in Atti di Convegno]
Guaitolini, S.; Franchi, I.; Generali, Luigi; Bertoldi, Carlo; Giannetti, Luca
abstract
RIASSUNTO
RAGIONI: L’uomo è esposto a due distinte forme di mercurio: il metilmercurio (CH3Hg) e l’etilmercurio (CH3CH2Hg+). Questo articolo riporta, attraverso l’analisi della letteratura, i possibili effetti sistemici causati dal mercurio proveniente dall’amalgama dentale.
MATERIALI E METODI: Attraverso l’analisi della letteratura si evince che il mercurio liberato dalle otturazioni in amalgama può determinare seri problemi neurologici.
RISULTATI: Tra i bersagli preferenziali del deposito di questo metallo si annoverano il sistema nervoso centrale e il rene.
CONCLUSIONI: I primi effetti dell’esposizione a lungo termine a vapori di mercurio sono non specifici; i sintomi possono iniziare pochi giorni dopo l’esposizione o possono passare molti anni dall’esposizione iniziale affinchè gli effetti tossici si manifestino.
Tra i danni neurologici più citati è stata riportata una correlazione fra amalgama presente nel cavo orale e patologie neurologiche degenerative.
ABSTRACT
BACKGROUND: The mercury pass along the food chain and, eventually, to man as methilmercury (CH3Hg) or ethilmercury (CH3CH2Hg+).
This article addresses the possibility that dental materials, specifically those including mercury, may be an important factor systemic diseases.
MATERIAL AND METHODS: dental amalgam mercury exposure results in neurologic disorders.
RESULTS: Human exposure to mercury results in neurologic and kidney disorder.
CONCLUSION:Several investigations have shown that elemental mercury vapour can be released from hardened dental amalgam, and it is directly related to the number of filling surfaces and may contribuite to neurologic disease.
2010
- Knowledge of the management of tooth avulsion by non-dental professionals in Modena, Italy.
[Abstract in Rivista]
MURRI DELLO DIAGO, Alberto; Generali, Luigi; Bertoldi, Carlo; Consolo, Ugo; Giannetti, Luca
abstract
Vedi allegato
2010
- La resezione dell’apice radicolare con strumenti piezoelettrici in endodonzia chirurgica: studio in vitro
[Relazione in Atti di Convegno]
Generali, Luigi; Franchi, I; Bertoldi, Carlo; Giannetti, Luca; Consolo, Ugo
abstract
RIASSUNTO
RAGIONI: L’evoluzione tecnologica degli ultimi anni ha fornito all’Odontoiatra strumenti piezoelettrici che permettono di intervenire sui tessuti duri eseguendo tagli di precisione micrometrica, di rispettare i tessuti molli e le strutture anatomiche e di ottenere siti operatori pressoché esangui. Gli Autori hanno sperimentato, nell’ambito dell’endodonzia chirurgica, la resezione dell’apice radicolare con inserti piezolettrici al fine di valutare la reale possibilità di utilizzare questa tecnologia come valido sostituto dei convenzionali strumenti rotanti.
MATERIALI E METODI: sono stati selezionati 30 elementi dentari monoradicolati estratti per motivi parodontali o ortodontici e poi suddivisi in 3 gruppi di 10 elementi dentari. È stata eseguita resezione dell’apice radicolare di ogni elemento dentario nel seguente modo:
Gruppo 1: resezione apice con manipolo anello rosso fresa Komet H269 314 016;
Gruppo 2: resezione apice con turbina fresa Komet H 269 314 016;
Gruppo 3: resezione apice con sorgente piezoelettrica Mectron inserto Mectron OT1.
I campioni sono stati processati per osservazione al microscopio elettronico a scansione al fine di valutare il numero e la tipologia di crack dentinali secondo la seguente scala:
- Numero di crack: A) assenza di crack; B) da 1 a 3; C) da 4 a 6; D) 7 e oltre;
- Tipologia di crack: completo, incompleto, intradentinale.
È stata effettuata analisi statistica con Test esatto di Fischer per valutare le differenze tra i gruppi.
RISULTATI: Non sono state apprezzate differenze statistiche tra i 3 gruppi.
CONCLUSIONI: l’assenza di differenze statistiche tra i tre gruppi dimostra la reale possibilità di utilizzare la tecnologia piezoelettrica come sostituto dei tradizionali strumenti rotanti convenzionali nella fase di resezione dell’apice radicolare in endodonzia chirurgica.
ABSTRACT
BACKGROUND:
In recent years, technology of has provided new piezoelectric devices which allow the dentist to focus on hard tissue by performing precision cuts micrometer, to respect soft tissues and anatomical structures and to obtain almost bloodless surgical sites. The authors have tested, focusing on endodontic surgery, cutting efficacy of piezoelectric inserts on the root apical tissue: the aim of the study was to compare piezoelectric devices to conventional rotary instruments in endodontic surgery.
MATERIAL AND METHODS:
30 monoradicular teeth were selected and extracted for orthodontic or periodontal reasons, and divided into 3 groups of 10 dental elements. Resection of the root apex of each tooth was performed as follows:
Group 1: apical resection with red ring handpiece, Komet H269 314 016 bur;
Group 2: apical resection with turbine, Komet H 269 314 016 bur;
Group 3: apical resection with Mectron piezoelectric device, Mectron OT1 insert.
The samples were processed for electronic scanning microscope observation in order to assess the number and type of dentinal crack using the following scale:
- Number of crack: a) absence of crack B) 1 to 3, C) from 4 to 6 d) 7 and beyond;
- Type of crack: complete, incomplete, limited to dentine structure.
RESULTS: There were no significant differences among the 3 groups.
CONCLUSION: The absence of statistical differences among the three groups demonstrated the possibility of using the piezoelectric technology as a substitute for traditional conventional rotary instruments during the surgical resection of the root apex in endodontic surgery.
2010
- L’adesione a perni in fibre di vetro pre-impregnate.
[Relazione in Atti di Convegno]
Pellacani, C.; Dotti, A.; Generali, Luigi; Bertoldi, Carlo; Giannetti, Luca
abstract
RIASSUNTO
RAGIONI: I perni endocanalare in fibre di vetro preimpregnae (FRC) presentano vantaggi biomeccanici rispetto ai tradizionali perni metallici (ad esempio le proprietà di flessione e una morfologia personalizzabile); per quanto concerne l’adesione alle resine composite, le analisi di laboratorio si sono concentrate soprattutto su prove di push-out, trascurando la mappatura delle tensioni che si generano sulla superficie della fibra.
MATERIALI E METODI:L'obiettivo di questo studio è stato quello di valutare l’adesione dei perni FRC nei confronti di un cemento in resina composita e un composito microibrido attraverso test di laboratorio. I provini sono stati realizzati interfacciando il perno FRC con un adesivo ed immergendo ciascuna estremità in un volume di cemento composito duale o composito per ricostruzioni per una lunghezza nota. Sui campioni sono state effettuate prove di sforzo di taglio a trazione (tensile shear stress) parallelamente all’asse lungo del perno. Il test terminava al momento della rottura dell’interfaccia tra perno e cemento composito, consentendo di apprezzare la forza massima di rottura di ciascun provino. La successiva analisi al Microscopio Elettronico a Scansione (SEM) ha evidenziato le caratteristiche morfologiche delle fibre dopo la rottura dell’interfaccia.
RISULTATI:Dai test di laboratorio si possono apprezzare elevate capacità di resistenza alla trazione dell’interfaccia tra i perni FRC ed entrambi i compositi, confermando l’affinità della matrice del sistema adesivo con la matrice del perno stesso. Le analisi al SEM sottolineano questo dato, mostrando una rottura all’interno del perno stesso piuttosto che nell’interfaccia tra i materiali impiegati.
CONCLUSIONI: Questo studio conferma le possibilità di applicazione delle fibre di vetro immerse in una matrice polimerica nel campo dei perni endocanalari non solo per il loro modulo elastico, ma anche in considerazione della loro affinità alla matrice in BisGMA dei compositi.
TITLE
ADHESION TO PRE-IMPREGNATED GLASS FIBER POSTS
ABSTRACT
BACKGROUND:
Fiber-reinforced composite (FRC) root canal posts have biomechanical advantages when compared to traditional metallic posts (i.e. flexural properties and a customizable framework); considering their adhesion to resin composites, laboratory analysis have mostly concentrated on push out tests rather than mapping tensile stress on the surface of the fiber.
MATERIAL AND METHODS:
The objective of this study was to evaluate the adhesion of FRC posts to composite resin cements and micro hybrid composite material through laboratory tests. Specimens were realized interfacing FRC posts with adhesive and dipping each end in a volume composite cement or micro hybrid composite for a known length. The specimens were test trough a pull out test parallel to the long axis of the posts (analyzing tensile shear stress). The test ended at the time of rupture of the interface between pin and cement composite, underlining the peak of rupture of each specimen. The subsequent analysis at the Scanning Electron Microscope (SEM) showed the morphological characteristics of the fibers after the rupture of the interface.
RESULTS:
Laboratory tests show high tensile capacity of the interface between FRC posts and composite, confirming the affinity of the matrix of the adhesive system with the matrix of the these fibers. SEM analysis emphasize this result, showing a break in the pin itself, rather than the interface between the materials used
CONCLUSION:
This study confirms the possibility to glass fibers with a polymer matrix as root canal post material not just because of their flexural properties, but also considering their analogy to composite BisGMA matrix.
2010
- Mini-implants in growing patients. A new protocol.
[Abstract in Rivista]
MURRI DELLO DIAGO, Alberto; Generali, Luigi; Bertoldi, Carlo; Consolo, Ugo; Giannetti, Luca
abstract
Vedi allegato
2010
- Mini-implants in growing patients: a case report.
[Articolo su rivista]
Giannetti, Luca; A. M., Dello Diago; F., Vecci; Consolo, Ugo
abstract
An immediate tooth replantation is the treatment of choice following avulsion, although it may not always be possible. The therapeutic approach is more complicated in patients that are still growing, as it must not interfere with normal cranial-facial growth processes. This case report evaluates the effectiveness of implant-prosthesis rehabilitation in a growing patient using mini-implants, following a failed post-avulsion tooth replantation. The accurate pre-surgical evaluation employed in this protocol, including the growth expectation assessment, made it possible to place the mini implants without interfering with subsequent sagittal and transversal growth of the maxillary bones. Two years of follow-up in the present case allowed us to confirm that this protocol resulted in a fast rehabilitation of the frontal section, with immediate aesthetic and functional success and patient's satisfaction.
2010
- Modified conservative and periodontal treatment in gingival buccal single recessions associated with non-carious lesions: a randomized clinical trial.
[Abstract in Rivista]
Lucchi, A.; Pellacani, C.; Bertoldi, Carlo; Allegretti, F.; Generali, Luigi; Giannetti, Luca; Consolo, Ugo
abstract
Vedi allegato
2010
- Multiple gingival recession treatment by coronally advanced flap alone or coronally advanced flap plus connective tissue graft: a randomized clinical trial.
[Abstract in Rivista]
Bertoldi, Carlo; Casto, C.; Pellacani, C.; Lucchi, A.; Generali, Luigi; Giannetti, Luca; Consolo, Ugo
abstract
Vedi allegato
2010
- Pulp extirpation for replanted avulsed teeth: a 6 years follow up.
[Abstract in Rivista]
MURRI DELLO DIAGO, Alberto; Generali, Luigi; Bertoldi, Carlo; Consolo, Ugo; Giannetti, Luca
abstract
Vedi allegato
2010
- Sealing ability of gutta-percha in root canals obturated by a modified continuous wave of condensation technique.
[Abstract in Rivista]
Generali, Luigi; Mancuso, R.; Travaglini, Domenico; Ardizzoni, Andrea; Giannetti, Luca; Bertoldi, Carlo; Ambu, E.
abstract
Vedi allegato
2010
- Single gingival recession treatment by coronally advanced flap alone or coronally advanced flap plus connective tissue graft: a randomized clinical trial
[Abstract in Rivista]
Bertoldi, Carlo; Spagnolo, L.; Dalmonego, S.; Lucchi, A.; Giannetti, Luca; Generali, Luigi; Consolo, Ugo
abstract
Vedi allegato
2010
- Temperature changes in guttapercha using two different heat sources: a preliminary in vitro study.
[Abstract in Rivista]
Generali, Luigi; Ambu, E.; DEL GIOVANE, Cinzia; Giannetti, Luca; Bertoldi, Carlo; Consolo, Ugo
abstract
Vedi allegato
2010
- The release of mercury from dental amalgam and potential systemic diseases: a letterature review.
[Abstract in Rivista]
Franchi, I.; Guaitolini, S.; Giannetti, Luca; Bertoldi, Carlo; Dotti, A.; Generali, Luigi
abstract
Vedi allegato
2010
- Trattamento di lesioni non cariose di V classe in associazione a chirurgia plastica mucogengivale.
[Relazione in Atti di Convegno]
Lucchi, A.; Bertoldi, Carlo; MURRI DELLO DIAGO, Alberto; Generali, Luigi; Giannetti, Luca
abstract
RIASSUNTO
Ragioni: Lo scopo di questo studio era valutare il trattamento clinico delle recessioni gengivali associate a lesioni non cariose di V classe trattate mediante otturazione in resina composita con lembo ad avanzamento coronale più innesto di gengiva cheratinizzata (CAF+CTG).
Materiali e metodi: Otto pazienti che presentavano recessioni gengivali di I e II classe di Miller, sono state trattate mediante il medesimo protocollo che consisteva in: - pretrattamento per elimanare fattori eziologici legati alla recessione -otturazione in composito - intervento di chirurgia parodontale (CAF+CTG) a 15 giorni di distanza. Le misurazioni cliniche svolte a T0 baseline e T1 (12mesi) comprendevano: Profondità di sondaggio (PD); Profondità della recessioni (Rec depth); Ampiezza della recessione (Rec width); Ammanco tissutale latero-mediale; Livello di attacco clinico (CAL);Ampiezza della gengiva cheratinizzata (KT); Ipersensibilità dentinale(IP); Presenza di un gradino (GRAD); un criterio qualitativo di soddisfazione estetica (S)
Risultati:
Il confronto longitudinale tra i dati raccolti aT0 (baseline) e a T1 (12 mesi) presentava una rilevanza statistica per i parametri Rec depth, Rec width, Rec thickness, CAL e presenza di gradino(GRAD), e un miglioramento della soddisfazione estetica per tutti i pazienti considerati. La ricopertura radicolare risultava essere pari a.89,6% SD19,8%.
Conclusioni: Tutti i casi trattati hanno mostrato un miglioramento dei parametri clinici considerati con un ottima soddisfazione estetica, supportando l’utilizzo di questa tecnica conservativo parodontale per il trattamentamento delle recessioni associate a lesioni non cariose.
ABSRACT
Background: The purpose of this study was to assess the treatment of gum recession associated with non-decaying lesions of V classed, treated by means of a resin filling composed of an advanced coronal flap, plus a graft of the keritanized gum (CAF + CTG).
Methods and Materials: Eight patients, for a total of eight gum recessions of Class I and II of Miller in association with enamel erosions, were treated using the same method, consisting of;
Pre-treatment to eliminate etiological factors relating to the recession.
Composite fillings.
Periodontal surgery (CAF + CTG) after fifteen days.
The clinical measurements are made to T0 baseline and T1 (12 months), comprising;
Depth of drilling (PD)
Depth of recession (Rec depth)
Width of recession (Rec width)
The absence of lateral-medial tissue
The severity of the treatment (CAL)
Width of keritanized gum (KT)
Hypersensitivity of the teeth
Presence of a step (GRAD)
A criteria qualitative if aesthetic satisfaction (S)
Results: The longitudinal comparison between the data collected from T0 (baseline) and from T1 (12 months) shows an important statistic for the parameters Rec depth, Rec width, Rec thickness, CAL and step presence, and an improvement in the aesthetic satisfaction for all the patients considered. The radicular covering resulted to be equal to 89.6% +SD19.8%
Conclusions: All the cases treated have demonstrated an improvement of the clinical parameters considered with an excellent aesthetic satisfaction, supporting the use of this conventional periodontal technique for the treatment of recessions associated with non-decaying lesions.
2010
- Trattamento di recessioni gengivali mediante chirurgia plastica mucogengivale in lesioni cariose di V classe.
[Articolo su rivista]
Bertoldi, Carlo; Lucchi, A.; Generali, Luigi; Pellacani, C.; Guaitolini, S.; Giannetti, Luca; Consolo, Ugo
abstract
Questo studio è diretto a valutare i risultati conseguibili mediante l’impiego di moderni criteri di previsione di rigenerazione tissutale che potrebbero permettere di anticipare efficientemente la fase conservativa su quella parodontale chirurgica.
Materiali e Metodi: Sono stati selezionati dei pazienti che presentavano recessioni di Miller di I e II classe associate a carie cervicale. La lesione cariosa è stata trattata mediante ricostruzione conservativa di V classe con l’utilizzo di compositi nanoriempiti previa valutazione del livello più fisiologicamente corretto di posizionamento della CEJ in previsione del futuro trattamento di chirurgia plastica mucogengivale.
Due settimane dopo la terapia conservativa è stato trattata la recessione mediante terapia chirurgica plastica mucogengivale mediante tecnica bilaminare costituita da coronally advanced flap con innesto connettivale come precedentemente descritto.
Il paziente è stato richiamato per sedute di controllo post-chirurgico a 1, 2, 3 e 4 settimane.
Le misurazioni cliniche sono state eseguite a T0 (baseline) e a T1 (12 mesi);
Risultati: Sono stati inclusi nello studio complessivamente 6 pazienti, di età compresa tra i 20 ed i 44 anni costituito da 3 individui di sesso femminile e 3 di sesso maschile. In particolare il confronto longitudinale tra i dati raccolti aT1 (baseline) e a T2 (12 mesi) presentava una rilevanza statistica di risoluzione clinica per i parametri Rec depth, Rec width, Rec thickness, CAL e presenza di gradino.
Conclusioni: La sola terapia conservativa così come quella parodontale non riescono a risolvere separatamente completamente il problema estetico in un elemento che presenta recessione e di conseguenza una corona clinica eccessivamente lunga. Per questo motivo è necessario utilizzare una tecnica combinata chirurgico-conservativa. Il nostro studio longitudinale dimostra che l’esecuzione conservativa anticipatamente alla fase chirurgica permette di poter agire in modo meno traumatico sui tessuti rigenerati e di aver a disposizione maggiori spazi per eseguire un restauro più preciso in rapporto al rispetto dei margini dente/materiale ed anche in correlazione ai parametri estetici del restauro stesso. Per converso un errore nella impostazione della fase conservative (soprattutto nella definizione corretta della CEJ) potrebbe portare ad una facile sottostima del problema recessorio e quindi ad una serie di facili quanto incongruenti “falsi” successi terapeutici.
2009
- Comparazione tra idrossiapatiti di derivazione sintetica e bovina su un modello animale.
[Abstract in Atti di Convegno]
Bertoldi, Carlo; Veneziani, A.; Zaffe, Davide; Giannetti, Luca; Consolo, Ugo
abstract
Vedi allegato
2009
- Effetto delle procedure di fusione sul misfit rotazionale di abutment UCLA.
[Abstract in Atti di Convegno]
Bortolini, Sergio; Malaguti, Giuliano; Giannetti, Luca; Bertoldi, Carlo; Consolo, Ugo
abstract
Vedi allegato
2009
- Novel CTSC mutations in a patient with Papillon-Lefevre syndrome with recurrent pyoderma and minimal oral and palmoplantar involvement
[Articolo su rivista]
Castori, M.; Madonna, S.; Giannetti, Luca; Floriddia, G.; Milioto, M.; Amato, S.; Castigla, D.
abstract
SIR, Papillon–Lefe`vre syndrome (PLS) is an autosomal recessivegenodermatosis mainly characterized by early-onset periodontitisand palmoplantar keratoderma. Recurrent pyogenic skininfections, usually of mild degree and self-healing, are relativelycommon additional features.1,2 PLS is caused by lossof-function mutations in the CTSC gene, which encodes forcathepsin C, a lysosomal cysteine protease required forthe activation of granule-associated serine proteases inimmune ⁄inflammatory cells.
2009
- Soluzioni di design per viti di connessione implantare: studio agli elementi finiti.
[Abstract in Atti di Convegno]
Forabosco, Andrea; Grandi, Tommaso; Grandi, Giovanni; Giannetti, Luca; Bertoldi, Carlo
abstract
Vedi allegato
2008
- Avulsione dentale e rivascolarizzazione pulpare in seguito a reimpianto: caso clinico.
[Articolo su rivista]
A., Murri; A., Odorici; Generali, Luigi; F., Vecci; Giannetti, Luca
abstract
Lo scopo di questo studio è quello di presentare un caso clinico di rivascolarizzazione pulpare in seguito a reimpianto dentale.Il paziente, di 9 anni, presenta entrambi gli incisivi centrali superiori avulsi in seguito ad un incidente sportivo.Giunge all’osservazione 30 minuti dopo il trauma, con gli elementi dentari conservati in soluzione fisiologica sin dai primi istanti. Entrambi gli elementi presentano apice beante e non completa formazione della radice.Seguendo le linee guida della IADT si decide di reimpiantare gli elementi e di eseguire uno splintaggio semi-flessibile.Si eseguono successivi controlli clinici e radiografici a 1-3-6-12 e 24 mesi.Nei denti con incompleta formazione radicolare è possibile andare incontro a rivascolarizzazione; tuttavia i test elettrici e termici non sono affidabili in seguito a traumi dentali, in quanto possono dare falsi negativi. La valutazione clinica di un dente traumatizzato però richiede uno studio sintomatico, visivo e radiografico. Se il dente diviene necrotico o infetto si può andare incontro ad un processo di riassorbimento radicolare che può condurre alla perdita del dente in breve tempo.Una diminuzione della dimensione della camera pulpare o del canale radicolare sull’immagine radiografica è un segno affidabile della vitalità pulpare.Il caso discusso rappresenta la possibilità di rivascolarizzazione in seguito a reimpianto a breve termine.
2008
- Comparative analysis of direct and indirect implant impression techniques an in vitro study
[Articolo su rivista]
Bambini, F.; Giannetti, Luca; Memè, L.; Pellecchia, L.; Selvaggio, R.
abstract
Implant impression and transfer of the implant position to a working cast for rehabilitative purposes not always represent a predictable reconstructive step. The variable results depend on the transfer technique utilized and on the accuracy of the impression materials. The aim of this study was to compare the accuracy of the direct and indirect impression techniques and to analyze the distortion of different impression materials. An edentulous acrylic resin mandible was used as reference model: in the cuspid position 2 laboratory analogs were inserted perpendicularly to the occlusal plane and fastened with resin. Two impressions for each indirect and direct recording techniques with 4 different impression materials were made. Polyvinyl siloxanes were used for the repositioning implant level method. Polyethers were used for the ''pick up'' impression technique. Analysis of cast distortion was measured computing the inter-implant position on the developed models compared to that of the master model. Measurements were recorded by a digital caliper. The results of this in vitro study demonstrate that the direct impression technique is preferable to the indirect one and that the Impregum polyether impression material is the most precise when used in association with a direct technique.
2008
- Condizionamento radicolare EDTA nel trattamento dei difetti intraossei mediante MIST.
[Abstract in Rivista]
Bertoldi, Carlo; Veneziani, A; Giannetti, Luca; Bencivenni, D.; Generali, Luigi
abstract
Vedi allegato
2008
- Crown fracture and stratification of composite restorations: replication of natural aesthetics
[Articolo su rivista]
Giannetti, Luca; MURRI DELLO DIAGO, Alberto
abstract
Presenting problemTraumatic dental injuries are frequent accidents that typically involve the maxillary anterior segment, where the most common injuries are crown fractures.Treatment of the dental trauma is complex and requires a comprehensive and accurate diagnostic and treatment plan.It is also important to consider the biological, functional, aesthetic and economic aspects, as well as the patient’s desire.Clinical managementThe success depends on a harmonious integration of various elements, including a thorough knowledge of the internal structure of natural dentition, aesthetics, characteristics of current materials, and restorative techniques.A natural appearing aesthetics result can be achieved in a relatively simple and predictable manner: anatomic stratification with successive layers of dentin, enamel, and incisal composite.General dentists might find the proposed techniques to be complicated and demanding because bonding techniques are still considered intricate, sensitive and unpredictable.This doubt can be overcome by the application of the “natural layering concept” which makes use of only two basic masses, dentin and enamel, perfectly mimicking natural tooth structure.The objective of this article is to present a personalized technique of stratification for each individual case in direct composite restorations.DiscussionThe presented protocol makes highly aesthetic restorations simple yet predictable. Identification and reproduction of the natural anatomy and nuance colour characteristics exhibited by natural dentition with composite resin, thought a detailed evaluation of hue, chroma, opalescence and fluorescence, allow the dentist to satisfy most aesthetic demands and it offers an interesting alternative, minimizing invasiveness, chair time and costs for patients.
2008
- Derivati proteici della matrice dello smalto ed il condizionamento radicolare mediante gel di acido etilendiamminotetraacetico nel trattamento rigenerativo dei difetti intraossei con principi di chirurgia minimamente invasiva: uno studio pilota.
[Articolo su rivista]
Bertoldi, Carlo; Zaffe, Davide; Bencivenni, D.; Giannetti, Luca; Lucchi, A.; Consolo, Ugo
abstract
Scopo del presente studio pilota, randomizzato e controllato è quello di comparare l’efficacia del condizionamento radicolare mediante acido etilendimminotetracetico (EDTA) nel trattamento di difetti intraossei profondi in termini di riduzione radiografica del difetto utilizzando tecniche di chirurgia minimamente invasiva.
Materiali e Metodi: Sono stati inclusi nello studio 8 pazienti sistemicamente sani, di età media di 40,88 ± 7,2 (compresa tra i 29 i 49 anni), nel gruppo TG1 l’età media era 40,05 ± 9,7 mentre net TG2 era 41,25 ± 5,1. I pazienti venivano scelti tra coloro che soffrivano di parodontite cronica moderata o grave. I soggetti selezionati dovevano presentare almeno un difetto intraosseo angolare maggiore di 6 mm al sondaggio (PPD) e con una componente intraossea radiologica maggiore a 3 mm. L’angolo del difetto doveva essere inferiore a 36°. Il difetto, inoltre, doveva avere una preponderante componente a 3 e a 2 pareti.
Lo studio poneva a confronto 2 differenti metodologie di trattamento; lo stesso accesso chirurgico, basato su principi di chirurgia minimamente invasiva e preservazione papillare, veniva attuato su difetti intraossei angolari. La scelta dei soggetti e quindi dei siti che dovevano essere sottoposti a condizionamento preventivo all’applicazione dei EMP (PrefGel & Emdogain, Straumann, Basel, Switzerland) con gel di EDTA al 24% (pH 6,7) (trattamento gruppo 1 - TG1) secondo le istruzioni del produttore e di quelli che sarebbero stati trattati con EMP senza preventivo condizionalmento (trattamento gruppo 2 – TG2), era basata su un criterio di randomizzazione semplice. Le misurazioni radiologiche, che costituiscono la base sperimentale del presente studio, erano eseguite mediante un centratore (Rinn, Dentsply, Weybridge, UK) reso individuale mediante un “bite” in silicone. Le valutazioni erano eseguite in fase iniziale (fase T0), immediatamente dopo l’intervento (T1), a 1 mese (T2) ed a 6 mesi dall’intervento (T3).
Venivano registrate le seguenti misure lineari:
- Profondità della componente intraossea del difetto (IBC) considerandola come la distanza verticale intercorrente (in mm) dalla cresta ossea al punto più apicale del difetto
- Angolo del difetto (DA); misurato in gradi e definito come l’angolo compreso tra il profilo della radice e la parete verticale ossea del difetto.
Risultati: Confrontando orizzontalmente, in rapporto all’IBC, i gruppi TG1 e TG2 tra loro nella fase iniziale (T0) così come nelle diverse fasi successive (T1, T2 e T3), il valore di P rimaneva maggiore di 0,06 per cui non si rilevavano tra essi differenze statisticamente significative. L’indagine statistica longitudinale attuata su TG1 presentava risultati significativi solo tra T1 e T4; lo stesso risultato statistico si otteneva dall’analoga valutazione del TG2.
Conclusioni: In questo studio pilota si è deciso di valutare a 6 mesi unicamente il parametro radiologico poiché alcune indicazioni sono emerse del tutto recentemente circa la possibile compromissione dei risultati rigenerativi conseguibili operando dei sondaggi antecedentemente ad un anno dall’intervento. Nel nostro studio abbiamo ottenuto risultati favorevoli a 6 mesi con entrambe le metodologie di intervento. Pur con i limiti insiti in uno studio pilota, i risultati emersi depongono per una “tendenza” rigenerativa decisamente marcata a 6 mesi dall’intervento mentre il potenziale contributo del condizionamento radicolare con gel di EDTA sulla rigenerazione della quota calcifica del difetto intraosseo non sembra significativo.
2008
- Derivati proteici della matrice dello smalto ed osso poroso di derivazione bovina nel trattamento rigenerativo dei difetti intraossei con principi di chirurgia minimamente invasiva: uno studio pilota.
[Articolo su rivista]
Bertoldi, Carlo; Zaffe, Davide; Lucchi, A.; Giannetti, Luca; Consolo, Ugo
abstract
Scopo del presente studio pilota, randomizzato e controllato è quello di comparare l’efficacia clinica dei soli derivati proteici della matrice dello smalto (EMP) rispetto all’associazione di EMP e derivati xenografici di osso bovino (BPBM) nel trattamento di difetti intraossei profondi in termini di riduzione radiografica del difetto utilizzando tecniche di chirurgia minimamente invasiva.
Materiali e Metodi: Sono stati inclusi nello studio 4 pazienti, di età media di 54,75 ± 7,9 (compresa tra i 44 e i 62 anni), due di sesso maschile e due di sesso femminile con difetti angolari soddisfacenti i criteri di inclusione in tutti i casi a livello premolare. I pazienti venivano scelti tra coloro che soffrivano di parodontite cronica moderata o grave.
Lo studio a split-mouth poneva a confronto 2 differenti strategie di trattamento; lo stesso accesso chirurgico, basato su principi di chirurgia minimamente invasiva e preservazione papillare, veniva attuato su difetti intraossei angolari nell’ambito della stessa arcata ma a split-mouth. La scelta del sito che doveva essere trattato con EMP (trattamento gruppo 1 - TG1) e, di conseguenza, di quello controlaterale trattato con EMP + BPBM (trattamento gruppo 2 – TG2), era basata su un criterio di randomizzazione semplice. Le misurazioni radiologiche, che costituiscono la base sperimentale del presente studio, erano eseguite mediante un centratore (Rinn, Dentsply, Weybridge, UK) reso individuale mediante un “bite” in silicone. Le valutazioni erano eseguite in fase iniziale (fase T0), immediatamente dopo l’intervento (T1), a 1 mese (T2) ed a 6 mesi dall’intervento (T3).
Venivano registrate le seguenti misure lineari: - Profondità della componente intraossea del difetto (IBC) considerandola come la distanza verticale intercorrente (in mm) dalla cresta ossea al punto più apicale del difetto - Angolo del difetto (DA); misurato in gradi e definito come l’angolo compreso tra il profilo della radice e la parete verticale ossea del difetto.
Risultati: L’analisi dei valori di IBC durante le fasi operative successive al baseline (dove vi era sovrapponibilità statistica tria i 2 gruppi) dava i seguenti risultati:
in faseT0 non rilevava significatività statistica tra TG1 e TG2, tale significatività era, invece, presente in fase T1 e T2 e, di nuovo, non si rilevava significatività in fase T3.
L’indagine longitudinale rispetto ai differenti gruppi presentava risultati significativi sia per TG1 che per TG2. Analizzando in dettaglio il risultato mediante test per confronti multipli risultava che nel TG1 si rilevava differenza significativa la fase T0 e la fase T3 e tra la fase T1 e la T3. Per quanto riguarda invece TG2 si verificavano differenze significative tra la fase T0 e la T1, tra la T0 e la T2 ma non per altre combinazioni di fasi come, ad esempio, tra T0 e T3.
Conclusioni: Nel nostro studio abbiamo ottenuto risultati favorevoli a 6 mesi con entrambe le tipologie di innesto. In TG1, nella fase T1, in termini assoluti e senza rilevanza statistica, si osservano risultati peggiori rispetto a T0; i valori, poi, migliorano sino a T3, fase in cui non si osservano significatività statistiche rispetto a T3 di TG2. In quest’ultimo gruppo, viceversa, in T1 si assiste a risultati, in termini assoluti, migliori che a T3, senza che, tuttavia, vi siano significatività statistiche nella comparazione tra T1 con T3 per TG2. I risultati emersi si sono dimostrati assai interessanti in quanto si è osservato che i soli EMP sarebbero in grado di garantire risultati radiologici sovrapponibili a quelli ottenibili con i BPBM in rapporto però a ben precise tipologie di difetto e con tecniche chirurgiche metodologicamente avanzate
2008
- Efficienza e qualità di taglio di due unità ultrasoniche dedicate all chirurgia oro-maxillo-facciale.
[Abstract in Rivista]
Travaglini, D.; Generali, Luigi; Giannetti, Luca; Bertoldi, Carlo; Consolo, Ugo
abstract
Vedi allegato
2008
- Evaluation of bio-ceramics in post-extraction site
[Articolo su rivista]
A., Odorici; A., Murri; D., Travaglini; Giannetti, Luca
abstract
Objectives: Extraction socket wound healing is characterized byresorption of the alveolar bone at the extraction site.The aim of this study is to investigate the clinical, radiographic,histological and histomorphometric effects of hydroxyapatitebone substitute on post-extraction wound healing.Methods: A total of 30 patients, who were referred for nonsurgical extractions of mandibular canine or premolar, wereincluded in the study. The relevant pre-operative informationswere recorded for each patient, included age and gender ofthe patient, indications for extraction, and tooth/teeth removed.Extractions were performed under local anesthesia with dentalforceps, elevators, or both. Patients were divided in 3 groups andevaluated at 4−8 and 12 months. A core of bone 3.5−12mm wasobtained from each patient.Results: Clinical evaluation: there was a good tissue integrationof the biomaterial; healing was uneventful in 30 alveoli (100%)and no healing complications were recorded.Radiographic evaluation: the hydroxyapatite showed a radioopacitysimilar to the surrounding bone.Histological evaluation: hydroxyapatite particle were observedin all specimens. Newly formed bone was characterized byabundance of cellular woven type bone in the coronal area whilelamellar arrangements could be identified only in the more apicalregion. New vital bone adhered to particles of residual graftmaterial.Histomorphometric evaluation: increase of mean bone tissue areaalong the histological sections were observed. Connective tissuefraction decrease from the crestal to the apical region.Conclusions: Hydroxyapatite bone substitute is an appropriatebiocompatible bone derivative in fresh extraction sockets for ridgepreservation.
2008
- Impacted third molar extraction: methylprednisolone or nimesulide
[Articolo su rivista]
C., Montosi; A., Murri; Bellini, Pierantonio; D., Travaglini; Giannetti, Luca
abstract
Objectives: The aim of this study was to evaluate the effect oftwo different drugs (methylprednisolone and nimesulide) to decreasethe swelling, pain and trismus after the surgical extractionof mandibular impacted third molars.Methods: This randomized clinical trial comprised thirty (30)adult patients of both genders (15 male and 15 female) withno local or systemic problems, with bilateral impacted lowerthird molars in similar position (Pell and Gregory’s class IIB),where surgical extraction had been indicated. These patientswere separated in two groups at random: the methylprednisolonegroup and the nimesulide group. A record card was filled inwith preoperative and postoperative epidemiological and clinicdata about inflammation, pain and trismus. The choice of whichside to operate first was made randomly and double-blindly. Theswelling was evaluated by ecography. The pain was evaluated byVAS modificated in GRS. The trismus was evaluated by interincisaldistance.Mean values were compared between the 2 groups with a 2-wayanalysis of variance and a Student’s t-test or the c2 test forqualitative comparisons. The threshold of significance was setat 5%.Results: Patients in the nimesulide group showed a moresevere swelling (p = 4.2175E-06) and a more severe trismus(p = 0.00034); pain was very similar in both groups.Conclusions: The results confirm the efficacy of methylprednisolonein providing a more comfortable postoperative courseafter surgical extraction of impacted lower third molars. It wasmore effective than nimesulide to reduce the degree of swellingand trismus. However, it had no clear effect on pain control.
2008
- Preemptive analgesia after impacted third molar extraction
[Abstract in Rivista]
Bellini, Pierantonio; F., Vecci; A., Dotti; Giannetti, Luca
abstract
OBJECTIVESThe aim of this study was to evaluate the effect of sodic naproxen as pre-emptive medication to decrease the post-operative pain after the surgical extraction of mandibular impacted third molars.METHODSThis randomized clinical trial comprised thirty (40) adult patients of both genders(20 male and 20 female) with no local or systemic problems, with bilateral impacted lower third molars in similar position (Pell and Gregory’s class IIB), where surgical extraction had been indicated. These patients were separated in two groups at random: the study group (naproxen 220 mg one hour before the extraction) and the control group (naproxen 220 mg at the end of the extraction). Both group received naproxen 220 mg 6 and 16 hours after the extraction.The pain was evaluated by VAS modified in GRS at 0, 6 and 16 h.Mean values were compared between the 2 groups with a 2-way analysis of variance and a Student’s t-test or the χ2 test for qualitative comparisons. The threshold of significance was set at 5%. RESULTSThe mean VAS values were 2.42±1.64, 3.17±1.75 e 2.52±1.51.Analysis of variance at 6 and 16 h after operation showed that there was less pain on the pre-emptive side (p< 0.001 and p< 0.023)while analysis of variance at 0 was not significant.CONCLUSIONSThe results confirm the efficacy of sodic naproxen in providing a more comfortable postoperative course after surgical extraction of impacted lower third molars.If used as pre-emptive medication sodic naproxen has an effective pain control.
2008
- Preservazione dell’alveolo post-estrattivo: valutazione clinica ed istologica di un materiale biomimietico.
[Abstract in Rivista]
Odorici, A.; Murri, A.; Bertoldi, Carlo; Travaglini, D.; Giannetti, Luca
abstract
L’obiettivo di questo studio è valutare clinicamente, radiograficamente e istologicamente il comportamento di un sostituto osseo di origine sintetica a base di idrossiapatite ad elevata porosità impiegato come riempitivo alveolare in seguito ad estrazione di elementi dentali monoradicolati.Sono stati selezionati 24 pazienti a cui è stato applicato il materiale suddetto; gli stessi sono stati suddivisi in tre gruppi e rispettivamente a 4, 8 e 12 mesi, ai fini della monitorizzazione dell’innesto, è stata effettuato un prelievo bioptico per analizzare istologicamente la tipologia del tessuto osseo presente nel sito d’innesto.Il materiale si è rivelato facilmente manipolabile e ha consentito un buon adattamento e una semplice compattazione nell’alveolo. Ha dimostrato una buona permanenza in situ sia durante che dopo le fasi di manipolazione chirurgica, consentendo un’agevole gestione e sutura dell’alveolo, migliorando il comfort per il paziente. Da un punto di vista clinico si è osservata una buona integrazione tessutale, in nessun caso infatti si è verificata una reazione avversa che potesse essere riconducibile all’utilizzo dei biomateriali.Radiograficamente, il materiale ha mostrato radiopacità del tutto sovrapponibile a quella dell’osso circostanteLe osservazioni istologiche testimoniano l’ottima biocompatibilità e le buone proprietà di osteointegrazione del biomateriale utilizzato in relazione all’osso di nuova formazione. L’intimo rapporto tra le particelle dei biomateriali e l’osso neoformato, nelle sue diverse fasi di formazione e mineralizzazione, consente di asserire la capacità osteoconduttiva del materiale, quale scaffold su cui viene a modellarsi il processo osteogenetico ricostruttivo.
2008
- Schöpf-Schulz-Passarge syndrome: Further delineation of the phenotype and genetic considerations
[Articolo su rivista]
Castori, M.; Ruggieri, S.; Giannetti, Luca; Annessi, G.; Zambruno, G.
abstract
Schöpf-Schulz-Passarge syndrome is a rare ectodermal dysplasia, characterized chiefly by multiple eyelid apocrine hidrocystomas, palmo-plantar keratoderma, hypodontia, hypotrichosis and nail dystrophy. The clinical spectrum and the most likely inheritance pattern(s) have not yet been completely defined. We report here on two, unrelated patients presenting with additional, previously unreported features, including hypoplastic nipples and optic atrophy. Both individuals were born to consanguineous parents, and one also has affected siblings. A literature review identified 23 additional cases. Multiple eyelid apocrine hidrocystomas, described in all of the cases, are the hallmark of this condition, although they usually appear in adulthood. The concomitant presence of eccrine syringofibroadenoma in most patients and of other adnexal skin tumours in 44% of affected subjects indicates that Schöpf-Schulz-Passarge is a genodermatosis with skin appendage neoplasms. However, the risk of skin and visceral malignancies is not increased. Pedigree study demonstrates that 9 of the 13 published familial cases may be explained by an autosomal recessive mutation, while the remaining pedigrees show apparent vertical transmission compatible with genetic heterogeneity. The benign disease course and advanced age at diagnosis could also suggest locus homogeneity for a recessive mutation with instances of pseudodominant inheritance.
2008
- Sopravvivenza del dente deciduo traumatizzato trattato endodonticamente:studio retrospettivo.
[Relazione in Atti di Convegno]
MURRI DELLO DIAGO, Alberto; F., Vecci; Giannetti, Luca
abstract
INTRODUZIONE La gestione del dente deciduo traumatizzato è argomento fortemente discusso e controverso.Gli studi presenti in letteratura presentano campioni di popolazione insufficienti per poter ottenere risultati statisticamente significativi.SCOPO DEL LAVORO Scopo del presente lavoro è quello di verificare i fattori che interferiscono con il successo del trattamento endodontico di denti decidui traumatizzati al fine di determinare il livello di successo del trattamento proposto attraverso un’analisi di sopravvivenza.MATERIALI E METODI Sono stati selezionati 53 pazienti, afferenti al Servizio di Traumatologia Dento-Alveolare dell’Università degli Studi di Modena e Reggio Emilia nel periodo gennaio 2004 – giugno 2008 per un totale di 67 elementi dentari decidui traumatizzati.Tutti i pazienti sono stati trattati secondo le linee guida della IADT e sottoposti a follow-up per un periodo di 48 mesiAl fine di valutare i fattori determinanti il successo terapeutico sono stati analizzati i seguenti parametri:1.età del paziente all’inizio del trattamento endodontico2.tipo di trauma3.tipo di riassorbimento patologico radicolare4.localizzazione del riassorbimento radicolare5.riassorbimento osseo6.alterazione dei tessuti molli7.condizione del tessuto pulpare8.trauma ricorrenteI valori ottenuti sono stati analizzati statisticamente tramite il chi-squared test.RISULTATI 23% dei pazienti valutati all’inizio del trattamento è di età inferiore ai 36 mesi.47.9% è incorso in un trauma di grado medio75% presenta un riassorbimento infiammatorio51 presenta un riassorbimento a livello apicale
2008
- Terzo molare incluso: preemptive analgesia?
[Articolo su rivista]
C., Montosi; A., Murri; D., Travaglini; F., Vecci; Giannetti, Luca
abstract
Il presente studio si pone l’obiettivo di valutare clinicamente la risposta algica alla preemptive analgesia, tramite FANS, nell’estrazione del terzo molare incluso.La coorte di pazienti selezionati, 12 uomini e 12 donne, rientra tra i pazienti giunti all’osservazione presso la Clinica Odontoiatrica dell’Università di Modena e Reggio Emilia nel biennio 2005-2007.Essi vengono suddivisi in tre gruppi da 8 pazienti ciascuno, A, B e C, in modo randomizzatoA tutti i pazienti viene somministrato naprossene sodico 220mg per os ½ ora prima dell’intervento.Nel gruppo A non si effettua una seconda somministrazione dopo l’intervento.Nel gruppo B si effettua una seconda somministrazione 3 ore dopo l’intervento.Nel gruppo C si effettua una seconda somministrazione 6 ore dopo l’interventoLa misura del dolore è stata eseguita mediante VAS a 3-6-9-12 ore.Le registrazioni VAS dimostrano un andamento similare in tutti i gruppi analizzati, nel gruppo B si osserva però maggiore omogeneità e linearità, mentre nel gruppo C si osserva un picco algico a 6 ore. Dall’analisi dei risultati si denota che il naprossene sodico è un ottimo presidio farmacologico, nell’ambito della chirurgia dei terzi molari inclusi, nella riduzione del dolore post-operatorio, se utilizzato sotto forma di preemptive analgesia.In particolar modo si evince che una seconda somministrazione a distanza di 3 ore dall’intervento permette di registrare valori algici progressivamente minori.
2008
- Trattamento rigenerativo dei difetti intraossei mediante chirurgia minimamente invasiva.
[Abstract in Rivista]
Bertoldi, Carlo; Giannetti, Luca; Guaitolini, S.; Generali, Luigi; Consolo, Ugo
abstract
Vedi allegato
2008
- Trauma dento alveolare complesso in zona estetica: proposta terapeutica.
[Abstract in Rivista]
Vecci, F.; Murri, A.; Bertoldi, Carlo; Montosi, C.; Giannetti, Luca
abstract
Lo scopo del presente lavoro è quello di presentare un caso clinico di trauma dento-alveolare complesso interessante il gruppo frontale.La paziente, S.X.L., di anni 40, giunge all’osservazione dello specialista circa un mese dopo il trauma avvenuto in seguito a incidente stradale.All’esame obiettivo, con l’ausilio di esami radiografici, si riscontra frattura radicolare a livello del terzo apicale di 2.1, accompagnata a lussazione di entrambi gli incisivi centrali, avulsione di 4.1 e 4.2 e frattura coronale non complicata di 3.1.Si decide di intervenire procedendo all’apecificazione del frammento coronale di 2.1 tramite Idrossido di Calcio e splintaggio semi-flessibile del gruppo frontale superiore; inferiormente si procede alla terapia endodontica dell’elemento 3.1 e alla realizzazione di un manufatto protesico provvisorio in resina applicato tramite nastro multistrato ultrafine in fibra di vetro.A distanza di un mese la paziente torna all’osservazione con persistente algia in zona 2.1; si decide quindi per l’estrazione dell’elemento dentario fratturato il quale viene modellato e utilizzato come elemento provvisorio nella fase di guarigione del sito post-estrattivo applicato tramite nastro multistrato ultrafine in fibra di vetro.La paziente risulta soddisfatta sia nell’estetica che nella funzione della riabilitazione adottata.La scelta terapeutica descritta permette una rapida risoluzione del trauma garantendo un’immediata estetica in una zona dagli importanti risvolti sociali ad un costo ridotto.
2008
- Utilizzo di impianti nell’avulsione dentaria dei pazienti in crescita: revisione della letteratura e proposta di nuovo protocollo terapeutico
[Articolo su rivista]
Giannetti, Luca; A., Murri; F., Vecci; Consolo, Ugo
abstract
Scopo del LavoroLo scopo del presente lavoro è quello di analizzare la letteratura di settore in merito all’implantologia osteointegrata nel paziente in crescita e di proporre e valutare l’efficacia di una riabilitazione implanto-protesica tramite mini-impianti in seguito a fallimento di reimpianto dentale post avulsione.Materiali e MetodiViene proposto un caso clinico giunto all’osservazione del Servizio di Traumatologia Dento-Alveolare dell’Università degli Studi di Modena e Reggio Emilia.Viene esposta l’accurata valutazione pre-operatoria necessaria all’identificazione dell’età scheletrica del soggetto.Viene quindi esposta la tecnica chirurgica e protesica.RisultatiA distanza di due anni non si osservano né clinicamente né radiograficamente segni di peri-implantite.Si riscontra un’ottima estetica e l’OHRQoL risulta fortemente positivo.ConclusioniIl presente studio amplia il panorama delle proposte terapeutiche in caso di fallimento di reimpianto dentale in soggetti in crescita evidenziando come la scelta dei mini-impianti permetta il raggiungimento del successo estetico e funzionale.
2007
- Avulsione dentaria e OHRQoL.
[Abstract in Rivista]
Murri, A.; Vecci, F.; Bertoldi, Carlo; Generali, Luigi; Giannetti, Luca
abstract
Scopo del presente lavoro è quello di descrivere l’OHRQoL su di una popolazione che è andata incontro ad avulsione dentaria. Lo studio inoltre si pone l’obiettivo di identificare evidenze cliniche, associate all’OHRQoL, e di identificare la riabilitazione ideale in seguito ad avulsione in pazienti minorenni.Lo studio rientra in un più ampio clinical trial effettuato presso l’Università degli Studi di Modena e Reggio Emilia nel triennio 2003-2006 che ha interessato una popolazione di 101 pazienti.Ciascun paziente ha ricevuto una precisa terapia, specifica per il singolo caso, laddove possibile si è intervenuti con il reimpianto immediato, laddove invece questi non era possibile, o era andato incontro a fallimento, si è intervenuti con differenti presidi.La popolazione di pazienti è stata sottoposta all’OHIP-14, indice della percezione di malattia sull’impatto sociale di affezioni orali.Si sono evidenziati 7 gruppi di studio indicanti le diverse tipologie di riabilitazione.Il 21.2% dei soggetti studiati ha riportato una o più risposte affermative all’OHIP-14 nei 12 mesi precedenti. Le percentuali più basse si sono riscontrate a carico dei pazienti con reimpianto immediato, mentre il maggior discomfort è stato rilevato a carico dei pazienti con chiusura ortodontica degli spazi. Le apparecchiature parziali adesive, tipo Maryland, o ricostruzioni con fibre di composito hanno dimostrato un certo livello di discomfort con valori pari al 20%.Gli apparecchi funzionali e le apparecchiature parziali rimovibili hanno invece dimostrato un buon livello di qualità della vita percepita, confermandosi quindi dei validi presidi, laddove il reimpianto non fosse possibile.
2007
- Correlazioni tra rischio parodontale ed indici sistemici di svantaggio sociale.
[Abstract in Rivista]
Bertoldi, Carlo; Lucchi, A.; Maretti, M.; Giannetti, Luca; Consolo, Ugo
abstract
Vedi allegato
2007
- Dental avulsion: therapeutic protocols and oral health-related quality of life.
[Articolo su rivista]
Giannetti, Luca; A., Murri; F., Vecci; R., Gatto
abstract
AIM: The aim of this study is to describe oral health-related quality of life (OHRQoL) among patients who have had a complete dislocation of the tooth out of its socket (tooth avulsion). The study also sought to identify clinical evidence, associated with OHRQoL, of the ideal therapeutic choice after tooth avulsion among these patients under 18 years old. STUDY DESIGN: 73 patients under 18 year old were selected between 101 studied; they received different treatments, after one year adverse impacts on OHRQoL were measured using the 14-item OHIP. RESULTS: Our findings show that if patients got into tooth avulsion their quality of life is adversely affected. In this study, 21.2\% of subjects reported 1 or more of the 14 OHIP items during the preceding 12 months, which is significantly high. In group A just 4\% of subjects reported 1 or more of the 14 OHIP items, while in the other groups the percentage rose, reaching 50\% in group F. Group C D G reported a value of 20\%, while in group E this is 12\%. CONCLUSION This study shows how different treatment options have different effects on quality of life; the ideal one is the immediate replantation, when this is not possible, RPD or functional appliance seem to be the best choice.
2007
- Enucleazione conservativa di un fibro-odontoma amelobblastico: caso clinico
[Articolo su rivista]
Generali, Luigi; Giannetti, Luca; Bellini, Pierantonio; Consolo, Ugo
abstract
■ Scopo del lavoro è quello di presentare la tecnica chirurgica utilizzata dagli Autori per l’asportazione, mediante utilizzo di microscopio operatorio, di una neoformazione gigante localizzata a livello del tuber mascellare ed estrinse- cantesi a livello del processo alveolare e nella cavità sinusale. La lesione è stata inquadrata istologicamente come fibro-odontoma ameloblastico.
2007
- Tooth avulsion: mini-implant rehabilitation in growing patients.
[Articolo su rivista]
Giannetti, Luca; A., Murri Dello Diago; F., Vecci; Consolo, Ugo
abstract
PRESENTING PROBLEM: The incidence of dental avulsion varies from 0.5 to 16% for permanent teeth and from 7 to 13% in deciduous teeth.The most affected age bracket is between 9 and 10 years, the period in which greatest craniofacial growth and development takes place.This causes considerable complexity in trauma management, as the therapeutic choice must suit this process without hindering it.Literature puts forward a number of different therapeutic possibilities such as Maryland Bridge, Removable Partial Denture, Orthodontic Space Closure and Autogenous Tooth Transplantation, all of which are valid from a functional and aesthetic point of view but that have an adverse effect on quality of life. Osteoingetrated implantation is not considered as an option as although no minimum age limit is established in literature for this type of rehabilitation, it causes ankylosis of the implant with consequent infraocclusion and therefore aesthetic and functional deficit.CLINICAL MANAGEMENT:This study aims to evaluate the effectiveness of a therapeutic approach through the use of mini-implants and immediate load implants.It presents two clinical cases of growing patients:ML aged 10, with avulsed 11 and 21, and KJ aged 14, with avulsed 11 and 12.Follow-up was performed at 3-6-12 and 24 months.DISCUSSION:The proposed technique made it possible to obtain rehabilitation of the traumatised frontal section in a single session, with immediate high aesthetic and functional success, and high patient satisfaction.Careful pre-operative study made it possible to plan surgery so as to not hinder the cranial-facial growth in process.The results at 24 months seem to confirm the initial assumption although further studies and follow-up will be required
2007
- Utilizzo di Mineral Trioxide Aggregate nella riparazione di perforazioni della forcazione: due casi clinici
[Articolo su rivista]
Generali, Luigi; Giannetti, Luca; Ambu, E.
abstract
Aims: Mineral Trioxide Aggregate (MTA), a Portland Cement-like materi- al, developed in 1993 by M. Torabine- jad, has been suggested in the treat- ment of furcal perforation. The aim of this study is to describe two case reports of teeth with furcal perforation treated with mineral trioxide aggre- gate.
Clinical cases: two molars with a furcal perforation, due to decay and iatro- genic mistake, respectively, were treated with Mineral Trioxide Aggregate during the conventional retreatment. Clinical and radiological controls show the healing of periodontal tissues.
Conclusions: the MTA seems to be the best material in the treatment of furcal perforation. Its excellent action may be connected with highly reduced quantity of liquid and bacterial leak- age, and this clinical condition seems to allow the healing of periodontal tissues.
2006
- Aesthetic rehabilitation after a dento-alveolar trauma with indirect composite reconstruction
[Articolo su rivista]
Giannetti, Luca; A., Murri; L., Gallottini; Generali, Luigi
abstract
The aim of this study is to present a technique to establish a functional and aesthetic rehabilitation after a dento-alveolar trauma with uncomplicated crown fracture and to establish a predictable reproduction of the natural anatomy and nuance colour characteristics exhibited by natural dentition.
2006
- Analisi al SEM sull’accumulo di placca in differenti fili di sutura.
[Abstract in Rivista]
Buffagni, S.; Murri, A.; Bertoldi, Carlo; Generali, Luigi; Giannetti, Luca
abstract
Lo scopo del presente lavoro è quello di esaminare l’accumulo di placca su differenti tipi di fili da sutura, comunemente usati in chirurgia orale, mediante una analisi al microscopio elettronico a scansione.Sono stati esaminati venti pazienti, che presentano la necessità di estrarre tre elementi dentari monoradicolati mandibolari e/o mascellari.Tutti i pazienti selezionati nello studio non presentano patologie sistemiche di rilievo non sono fumatori ed il range di età è compreso tra i 30 e 50 anni.Si provvede ad impostare un protocollo igienico finalizzato volto al raggiungimento di un GI = 0 ed un PLI = 0 in modo tale da ridurre l’Alpha Error Level. In seguito all’estrazione degli stessi si suturano i tre alveoli rispettivamente con: Seta 3/0, Polyglactin 910 3/0, Poliglecaprone 3/0. A distanza di sette giorni si provvede alla rimozione delle suture, le si processa e le si esamina al microscopio elettronico a scansione. Per ciascun campione analizzato si valuta la presenza di placca batterica, di cellule sanguigne, di detriti e di microrganismi.Si osservano significative differenze tra i fili da sutura monofilamento rispetto ai plurifilamento, questi ultimi infatti presentano un evidente strato di placca batterica. Tra i fili plurifilamento utilizzati nel nostro studio emerge che il Polyglactin 910 risulta meno contaminato rispetto alla seta.
2006
- Bio-oss ed idrossiapatite nella riparazione di difetti ossei: studio preliminare.
[Abstract in Rivista]
Bertoldi, Carlo; Zaffe, Davide; Bellini, Pierantonio; Giannetti, Luca; Consolo, Ugo
abstract
Vedi allegato
2006
- Caries prevention about inorganic fluoride: a SEM investigation.
[Articolo su rivista]
Chelariu, C; Giannetti, Luca; Milia, E; Gallottini, L.
abstract
AIM To investigate the adaptation of new generation fiber post compared with prefabricated glass fiber postsMATERIAL AND METHODS The experiment was performed by two experienced clinicians, the former performed endodontic therapies and the latter post restorations. The clinical crowns of twenty human extracted teeth were sectioned at the cemento-enamel junction. The canals were shaped with MTwo NiTi rotary files up to 25 .07. Root canals were filled with guttapercha points with vertical condensation technique up to 5 mm to the apex. The middle and coronal part of the canal were cleaned with GG burs 1-4, used with very light touch. Adhesion technique, using 4th generation adhesives was performed. With a random number generator, at this point the roots were divided into two groups, 10 teeth each, A and B; group A was restored with a prefabricated fiber post, group B with a new generation Ever-stick post, made of preimpregnated fibers that can be packed into the canal. Both types of posts were cemented with flowable auto-photo composite, which was allowed to set for 15 minutes.The roots were then sectioned 3 mm from the coronal end with a rotating disk, polished and photographed with a camera on a fixed mount. The images were processed with software that allowed to measure the cement thickness from fibers to dentin, with 8 measures for each specimen. The numeric data were processed with a statistical program in order to evaluate differences between groups and its significance (quantitative analysis).Qualitative analysis was performed by two experienced independent observers, the accordance of whom was evaluated with Cohen K test, that gave to each specimen a score 0-3, accordingly to the presence or absence of defects, such as voids in the material or lack of adherence to dentinal walls. Kruskal-Wallis and Mann-Whitney tests were used to identify differences in the groups.RESULTS New generation fiber posts are a valuable alternative to preformed fiber posts.
2006
- Clinical evidence and literature to compare two different therapeutic protocols in tooth avulsion.
[Articolo su rivista]
Giannetti, Luca; A., Murri
abstract
AIM: This is to assess the priority in tooth avulsion: replantation as quickly as possible and deferred endodontic treatment, or replantation and elimination of every irritating stimulus for the periodontal ligament. The objective is to establish a univocal protocol by analysing and comparing the various components of these therapeutic procedures. MATERIALS AND METHODS: Study design: 20 patients were selected and divided into 2 groups: in group A we focused our attention on the rapidity of replantation, in group B we focused on the elimination of the necrotic pulp and every possible irritating stimulus that might lead to root resorption of inflammatory nature. RESULTS: Clinically, dental mobility seems to be greater in the first group. However after 15 days teeth have a comparable mobility and after one month they all show a mobility degree 1. Radiographically a greater incidence of resorption can be observed in group A compared to group B as in the first one a higher number of replanted teeth undergo resorption. Such lesions have the tendency to remain constant or even increase. CONCLUSIONS: The results of this study seem to take only one direction: extraoral endodontic therapy.
2006
- Direct pulp capping with mineral trioxide aggregate in a permanent molar: a case report
[Articolo su rivista]
Giannetti, Luca; Tozzi, S.; Murri, A.; Bertani, P.; Gallottini, L.
abstract
Si presenta un caso clinico di incappucciamento diretto a carico di un primo molare inferiore di destra, 4.6, con esposizione pulpare in seguito a carie, di una paziente di 9 anniIl materiale scelto per l’incappucciamento è un materiale alcalino a base di mineral trioxide aggregate (MTA).Non sono stati riscontrati segni patologici né radiograficamente né clinicamente a nessuno dei controlli eseguiti a 3-6 e 12 mesi.L’elemento dentario è rimasto sempre vitale in seguito all’incappucciamento con MTA.Ulteriori investigazioni cliniche sull’utilizzo dell’MTA come materiale da incappucciamento diretto, in seguito ad esposizione pulpare per carie, dovrebbero essere eseguite.
2006
- Effectivness of cleaning procedures on rotary nickel-titanium files: a SEM analysis.
[Articolo su rivista]
Generali, Luigi; Ciacci, L; Generali, P; Giannetti, Luca; Dettori, C.
abstract
AIM:The purpose of the present study was to quantify the surface debris on endodontic nickel-titanium rotary files after cleaning procedures.MATERIALS AND METHODS:Rotary nickel-titanium files (ProFiles and MTwo) were examined after removal from the packaging, after instrumentation in human teeth, and after various cleaning procedures. The cleaning procedures consisted of either ultrasonication with the files placed in a perforated container or ultrasonication with the files loosely placed in a beaker, with various cleaning agents. The presence of debris was evaluated using scanning electron microscopy. Specimens were scored accordingly to a 0-4 scale by two independent observers, whose agreement was previously evaluated using Cohen-K test. Data were analyzed with Kruskal Wallis and Mann-Whitney test for significativity. RESULTS:Some files were delivered from the factory with machining debris. The effectiveness of cleaning procedures with or without enzymatic products was different with p<0,001. Cleaning the files by ultrasonication within a container did not consistently achieve complete removal of debris. Placing the files loosely in the ultrasonic bath achieved the most effective cleaning.CONCLUSIONS:A conventional cleaning method is capable of effectively removing debris from endodontic files.
2006
- Fibro-odontoma ameloblastico localizzato nel seno mascellare: caso clinico
[Abstract in Rivista]
Generali, Luigi; Bellini, Pierantonio; Giannetti, Luca; Generali, P.; Consolo, Ugo
abstract
Vedasi l'allegato
2006
- Il controllo dell’edema nella chirurgia degli ottavi inclusi.
[Abstract in Rivista]
Magagna, F.; Murri, A.; Bertoldi, Carlo; Piacente, M.; Giannetti, Luca
abstract
L’utilizzo dei corticosteroidi in chirurgia orale è un presidio farmacologico abbastanza diffuso, ma privo di una letteratura chiara in merito alla reale efficacia , all’applicazione clinica, al tipo di steroide, al dosaggio e alla durata della somministrazione. Il presente studio si prefigge lo scopo di indagare gli effetti della somministrazione di questo farmaco nel decorso pre e post operatorio nella chirurgia degli ottavi inclusi.Sono selezionati 30 pazienti che necessitano dell’estrazione di entrambi i terzi molari inferiori; per il primo viene somministrata una terapia antibiotica associata a corticosteroidi, mentre per il secondo una terapia antibiotica associata ad un antinfiammatorio non steroideo.Al fine di valutare l’effetto antiedemigeno del farmaco viene eseguita, prima di entrambi gli interventi, un’ecografia in corrispondenza della regione in cui verrà successivamente estratto l’elemento dentario ed una seconda ecografia nella stessa sede due giorni dopo l’intervento.Si osserva un’evidente riduzione dell’edema post-operatorio nel gruppo associato al cortisonico, nonché una riduzione del trisma e del dolore, valutato tramite scala VAS.Basandosi su questi valori l’utilizzo dei corticosteroidi appare una metodica sicura e razionale volta alla riduzione delle complicanze post-operatorie in seguito ad estrazione di terzi molari inclusi.
2006
- Nuovo disegno di pin/vite riassorbibile per fissaggio di membrane
[Abstract in Rivista]
Bellini, Pierantonio; Giannetti, Luca; Travaglini, Domenico; Ciacci, L.; Consolo, Ugo
abstract
Vedasi l'allegato
2006
- Positività HSV ed insuccessi nella terapia delle recessioni: cases report.
[Abstract in Rivista]
Bertoldi, Carlo; Barbolini, Giuseppe; Bencivenni, D.; Bellini, Pierantonio; Giannetti, Luca
abstract
Vedi allegato
2006
- Preemptive analgesia nell’estrazione dell’ottavo incluso.
[Articolo su rivista]
Barbieri, Alberto; Giannetti, Luca; Pinna, Cristina; A., Murri; Piacente, Marco
abstract
Objective: valutare l’effetto della somministrazione preemptive dell’analgesico, nello specifico naprossene sodico a basso dosaggio (220 mg), nell’estrazione dell’ottavo incluso.Material and methods: sono stati studiati 20 pazienti da sottoporre ad estrazione dell’ottavo incluso inferiore bilaterale suddivisi in due gruppi (gruppo 1: 1 compressa di naprossene sodico 220 mg 1 ora prima dell’intervento; gruppo 2: 1 compressa di naprossene sodico 220 mg al termine dell’intervento; gruppi 1 e 2: 1 compressa di naprossene sodico 220 mg dopo 6 e dopo 16 ore dalla fine dell’intervento). La misura del dolore è stata eseguita mediante VAS mentre lo stato psicologico è stato valutato attraverso il Symptom Rating Test.Results: l’elaborazione dei SRTs ha mostrato omogeneità e normalità del campione. Il VAS medio dei due interventi nei tre tempi era di 2.42±1.64, 3.17±1.75 e 2.52±1.51. Il confronto tra i VAS nei soggetti sottoposti a preemptive e i non trattati mostrato una tendenza alla significatività. Nei soggetti sottoposti a tale tecnica nella seconda seduta il confronto è risultato significativo.Conclusions: i VAS medi di tutti i pazienti erano bassi e molto inferiori al limite per eventuali rescue medication; il farmaco impiegato è risultato pertanto efficace ed anche sicuro non essendo stati riscontrati effetti indesiderati. La preemptive analgesia, inoltre, è risultata utile poiché il dolore nei pazienti trattati con essa era inferiore ai non trattati.
2006
- Realizzazione di manufatto protesico provvisorio post-estrattivo preimplantare diretto; caso clinico.
[Abstract in Rivista]
Tozzi, S.; Bertani, P.; Generali, P.; Giannetti, Luca; Consolo, Ugo
abstract
Vedasi l'allegato
2006
- Rivascolarizzazione pulpare in seguito a reimpianto dentale: caso clinico.
[Articolo su rivista]
F., Magagna; MURRI DELLO DIAGO, Alberto; Generali, Luigi; E., Ambu; Giannetti, Luca
abstract
INTRODUZIONE E SCOPO DELLO STUDIO In seguito ad avulsione dentaria il processo di guarigione del fascio vascolo-nervoso determina il piano terapeutico.Studi effettuati sulla reazione della polpa hanno permesso di identificare diversi processi di guarigione.Numerosi studi eseguiti hanno portato ad osservare la formazione di tessuto duro lungo le pareti dentinali circa 17 giorni dopo il reimpianto; mentre si osservano nuove fibre nervose circa un mese dopo. Studi di tipo microangiografico hanno dimostrato la presenza di nuovi vasi già a 4 giorni dal reimpianto; dopo 10 giorni sono stati rilevati vasi nel terzo apicale e dopo 30 giorni nell’intera camera pulpare. Lo scopo di questo studio è quello di presentare un caso clinico di rivascolarizzazione pulpare in seguito a reimpianto.MATERIALI E METODI Il paziente, di 8 anni, presenta entrambi gli incisivi centrali superiori avulsi in seguito ad un incidente sportivo.Giunge all’osservazione 30 minuti dopo il trauma, con gli elementi dentari conservati in soluzione fisiologica sin dai primi istanti. Entrambi gli elementi presentano apice beante e non completa formazione della radice.Seguendo le linee guida della IADT si decide di reimpiantare gli elementi e di eseguire uno splintaggio semi-flessibile.Si eseguono successivi controlli clinici e radiografici a 1-3-6 e 12 mesi.CONCLUSIONI Nei denti con incompleta formazione radicolare è possibile andare incontro a rivascolarizzazione; tuttavia i test elettrici e termici non sono affidabili in seguito a traumi dentali, in quanto possono dare falsi negativi. La valutazione clinica di un dente traumatizzato però richiede uno studio sintomatico, visivo e radiografico. Se il dente diviene necrotico o infetto si può andare incontro ad un processo di riassorbimento radicolare che può condurre alla perdita del dente in breve tempo.Una diminuzione della dimensione della camera pulpare o del canale radicolare sull’immagine radiografica è un segno affidabile della vitalità pulpare.Il caso discusso rappresenta la possibilità di rivascolarizzazione in seguito a reimpianto a breve termine.
2006
- Stabilizzazione delle recessioni con tecniche subepiteliali: studio pilota.
[Abstract in Rivista]
Bertoldi, Carlo; Lucchi, A.; Bencivenni, D.; Giannetti, Luca; Consolo, Ugo
abstract
Vedi allegato
2006
- Studio epidemiologico sulla prevalenza della patologia cariosa nella popolazione scolastica modenese
[Articolo su rivista]
Giannetti, Luca; A., Murri; F., Vecci
abstract
Nel 1979 il WHO e il FDI World Dental Federation annunciarono gli obiettivi per la salute orale: 6 goals entro l’anno 2000 tra cui si poneva particolare attenzione alla patologia cariosa nei pazienti in età pediatrica, all’età di 12 anni infatti è possibile effettuare uno studio a larga scala, in quanto si è ancora nelle scuole dell’obbligo e si è completata l’eruzione dei permanenti ad eccezione dei terzi molari.La prima mappa globale fu presentata nel 1969 mostrando la prevalenza di carie nei paesi industrializzati e nei paesi in via di sviluppo.Da allora ad oggi si sono susseguiti molteplici studi che permettono di avere un database a livello mondiale molto accurato.Il presente studio si inserisce in questa scia e vuole cercare di dare un quadro della situazione modenese riprendendo i parametri e le metodologie proposte dal WHO.
2006
- Terapia endodontica in seguito ad avulsione dentaria: revisione della letteratura.
[Articolo su rivista]
MURRI DELLO DIAGO, Alberto; Generali, Luigi; E., Ambu; Giannetti, Luca
abstract
INTRODUZIONE E SCOPO DELLO STUDIO In seguito al reimpianto di un elemento dentario avulso è facile incorrere in processi infettivi e di riassorbimento. A tal proposito critica è la condizione endodontica; la polpa necrotica può infatti facilmente infettarsi. Un’adeguata terapia endodontica si rileva quindi fondamentale per impedire o arrestare le possibili complicanze. Questo studio si pone l’obiettivo di eseguire una revisione sistematica della letteratura e di valutare quale debba essere la corretta gestione endodontica in seguito a reimpianto.MATERIALI E METODI Si esegue una ricerca della letteratura ponendo come domanda chiave quale debba essere la terapia endodontica del dente avulso e reimpiantato.Utilizzando quindi il catalogo MeSH si restringe il campo di ricerca tramite il termine booleano AND e lo si limita ai Major Topics. La stringa ottenuta viene applicata a PubMed.Gli item ricavati vengono sottoposti quindi ad una ulteriore analisi effettuata tramite valori descritti dal Center for Evidence-Based Medicine e dal Clinical Appraisal Skill Programme del National Health Service (UK).CONCLUSIONI La revisione della letteratura di tipo sistematico permette di vagliare oggettivamente la moltitudine di articoli oggi disponibili rendendo quindi più semplice il compito al clinico che quotidianamente affronta le diverse tematiche.Questo studio ha posto un quesito che è però rimasto irrisolto, in quanto la terapia endodontica dell’elemento avulso con dry-time > 1 ora permane argomento di discussione.Esiste una dicotomia tra chi sostiene la necessità di intervenire extra-oralmente e chi invece intra-oralmente. Si pone quindi la necessità di eseguire ulteriori studi clinici con rigidi protocolli.
2006
- Trauma dento-alveolare complesso: case report.
[Abstract in Rivista]
Murri, A.; Bertoldi, Carlo; Tozzi, S.; Bertani, P.; Giannetti, Luca
abstract
Lo scopo del presente lavoro è quello di presentare un caso clinico di trauma dento-alveolare complesso interessante il gruppo frontale superiore.La paziente, C.S., di anni 22, giunge all’osservazione dello specialista trenta minuti dopo il trauma sportivo.All’esame obiettivo, con l’ausilio di esami radiografici, si riscontra avulsione di 1.2, conservato da subito in soluzione salina, e sub-lussazione, con frattura coronale non complicata, di 11.Si decide di intervenire reimpiantando l’elemento avulso, quindi splintando l’intero gruppo frontale in composito e filo ortodontico in acciaio.A distanza di una settimana si eseguono pulpectomia e medicazione con idrossido di calcio di1.2. A due settimane si esegue la terapia canalare dello stesso, e, considerata la risposta negativa al test di vitalità pulpare, la si esegue anche a carico del 1.1. Si rimuove lo split e si riscontra una stabilità fisiologica di tutti gli elementi.Si decide per una ricostruzione diretta, di tipo intercettivo, a carico del 1.1 in attesa di una situazione endodontica stabilizzata.A distanza di tre mesi non si riscontrano lesioni periapicali, né riassorbimenti radicolari, e si decide di intervenire a carico dell’ 1.1 con un restauro adesivo indiretto, garantendo un migliore risultato estetico.A distanza di sei mesi la situazione rimane costante, così come a distanza di un anno.Con questo studio si è così osservata una procedura, in linea con le indicazioni internazionali, che ha permesso di raggiungere il successo clinico, garantendo sia un risultato funzionale che estetico.
2006
- Traumatologia dentale e dento-alveolare:diagnosi, tratatmento e prognosi.Dossier
[Articolo su rivista]
Forabosco, A.; Giannetti, Luca; Grandi, T.
abstract
In questo breve dossier viene presentata la diagnosi il trattamento e la prognosi in traumatologia dentale e dento-alveolare
2006
- Traumatologia dentale e dentoalveolare
DIAGNOSI, TRATTAMENTO E PROGNOSI
[Articolo su rivista]
Forabosco, A.; Giannetti, L.; Grandi, T.
abstract
Traumatic dental injuries: diagnosis, treatment and prognosis
Dental trauma in children and adolescents is a common problem as the prevalente of these injuries has increased in the last 20 years. The Authors underline the importante of early diagnosis and correct treatment to improve prognosis and to restore dental and facial aesthetics.
Both new technologies and an improved understanding of inflammatoty process have led to a more conservative approach in treating dental trauma. Treatment protocols for both simple and more complex dental trauma are shown.
Because the management of injunes of deciduous teeth significantly difers from that of permanent teerh, separate guidelines have been developed. In particular the Authors focus their attention on two different aspects: the mechanisms of pulp and periodontal healing and the prognosis of such tissues after different traumatic dental injuries,
2006
- Valutazione al SEM di file endodontici dopo procedure di detersione
[Articolo su rivista]
Generali, Luigi; Ambu, E.; Giannetti, Luca; Murri dello, Diago; Generali, P.
abstract
Il presente lavoro valuta la morfologia dei file endodontici dopo aver subito dievsre procedure di detersione
2006
- Valutazione del successo implantare in rialzi di seno e innesti additivi
[Abstract in Rivista]
Orlandi, A.; Bencivenni, D.; Giannetti, Luca; Bellini, Pierantonio; Consolo, Ugo
abstract
Vedasi l'allegato
2005
- Comparative analysis of direct and indirect implant impression techniques an in vitro study. An in vitro study.
[Articolo su rivista]
Bambini, F; Giannetti, Luca; Memè, L; Pellecchia, M; Selvaggio, R.
abstract
Implant impression and transfer of the implant position to a working cast for rehabilitative purposes not always represent a predictable reconstructive step. The variable results depend on the transfer technique utilized and on the accuracy of the impression materials. The aim of this study was to compare the accuracy of the direct and indirect impression techniques and to analyze the distortion of different impression materials. An edentulous acrylic resin mandible was used as reference model: in the cuspid position 2 laboratory analogs were inserted perpendicularly to the occlusal plane and fastened with resin. Two impressions for each indirect and direct recording techniques with 4 different impression materials were made. Polyvinyl siloxanes were used for the repositioning implant level method. Polyethers were used for the ''pick up'' impression technique. Analysis of cast distortion was measured computing the inter-implant position on the developed models compared to that of the master model. Measurements were recorded by a digital caliper. The results of this in vitro study demonstrate that the direct impression technique is preferable to the indirect one and that the Impregum polyether impression material is the most precise when used in association with a direct technique.
2005
- Confronto tra due tecniche sub-epiteliali nel trattamento delle recessioni gengivali.
[Abstract in Rivista]
Bertoldi, Carlo; Lucchi, A.; Bencivenni, D.; Giannetti, Luca; Consolo, Ugo
abstract
Vedi allegato
2005
- Guarigione dei siti post-estrattivi nei pazienti leucemici: studio preliminare.
[Abstract in Rivista]
Bertoldi, Carlo; Narni, Franco; Ciacci, L.; Giansoldati, L.; Giannetti, Luca
abstract
Vedi allegato
2005
- Il sovrannumerario dentario, valutazione e presentazione di un caso.
[Abstract in Rivista]
Giansoldati, L.; Bertoldi, Carlo; Micucci, N.; Giannetti, Luca; Bellini, Pierantonio
abstract
Vedi allegato
2005
- Incremento di gengiva cheratinizzata mediante innesti subepiteliali.
[Abstract in Rivista]
Bertoldi, Carlo; Lucchi, A.; Bencivenni, D.; Giannetti, Luca; Consolo, Ugo
abstract
Vedi allegato
2005
- La prevalenza della patologia periapicale nei denti trattati endodonticamente
[Articolo su rivista]
Ciacci, L.; Bertani, P.; Giannetti, Luca; Bellini, Pierantonio; Tozzi, S.; Generali, P.
abstract
Il presente lavoro mostra come vi sia una prevalenza di patologia periapicale nel cavo orale di pazienti trattati endodonticamente.
2005
- Ozonoterapia in pedodonzia; nuovo trattamento per le carie dei decidui.
[Abstract in Rivista]
Giannetti, Luca; Olivi, F.; Bertani, P.; Bertoldi, Carlo; Consolo, Ugo
abstract
Vedi allegato
2005
- Ozonoterapia: nuova tecnica per il trattamento della carie dentale.
[Abstract in Rivista]
Giannetti, Luca; Olivi, F.; Bertani, P.; Bertoldi, Carlo; Magagna, F.
abstract
Vedi allegato
2005
- Ricostruzione di un elemento dentario vitale riposizionando il frammento coronale.
[Abstract in Rivista]
Giannetti, Luca; Buffagni, S.; Bertoldi, Carlo; Piacente, M.; Magagna, F.
abstract
Vedi allegato
2005
- Ricostruzione post-endodontica con perni in fibra
[Articolo su rivista]
Tozzi, S.; Generali, P.; Bertani, P.; Giannetti, Luca; Bellini, Pierantonio; Ciacci, L.
abstract
Il presente lavoro valuta la ricostruzione post-endodontica utlizzando perni in fibra.
2005
- Trattamento della baby-bottle sindrome con ozonoterapia.
[Abstract in Rivista]
Giannetti, Luca; Olivi, F.; Bertani, P.; Bertoldi, Carlo; Buffagni, S.
abstract
Vedi allegati
2005
- Un nuovo disegno di vite per innesti autologhi in blocchi.
[Abstract in Rivista]
Consolo, Ugo; Giannetti, Luca; Bertoldi, Carlo; Ciacci, L.; Bellini, Pierantonio
abstract
Vedi allegato
2004
- Actinomicetoma del mascellare superiore: due casi clinici
[Abstract in Rivista]
Generali, Luigi; Lucchi, A.; Ambu, E.; Giannetti, Luca; Consolo, Ugo
abstract
Vedasi l'allegato
2004
- Apoptosis: Escaping strategies in human skin cancer (Review)
[Articolo su rivista]
Giannetti, Luca; Consolo, Ugo; Magnoni, Cristina; Lorenzo Lo, Muzio
abstract
Apoptosis must be considered a rescue mechanism that controls the integrity of the cell erasing aberrant clones and it is likely that failure of apoptosis constitutes a key factor responsible for tumour formation, progression and resistance to drugs. Several genes (e.g. survivin, bcl-2 family, p53) are involved in these pathways. Much work still needs to be done to identify the molecular pathway of apoptosis resistance but restoration of the apoptotic response represents a crucial new therapeutic target for cancer treatment.
2004
- Drugs in oral surgery. Brief guidelines for adult patients.
[Articolo su rivista]
R. F., Grassi; S., Pappalardo; M., De Benedittis; M., Petruzzi; Giannetti, Luca; V., Cappello; O. A., Baglio
abstract
Drugs administrable in oral surgery for adult patients are antiseptics-antibiotics, antiinflammatory-analgesics and sedative-hypnotics. Such drugs can be administered before, during or after oral surgery. Sedative-hypnotics can be administered before or during oral surgery in order to control the patient's anxiety. Anti-inflammatory-analgesics, on the other hand, can be administered before or after oral surgery to lower edema and pain. For this purpose, FANS are the most commonly used drugs but, in more traumatic oral surgery, the administration of a single pre-surgery dose of corticosteroids is suitable. As regards, antibiotics have to be given from 15 min to 1 h before oral surgery and continued or otherwise for 24-48 h depending on the dosage. post-surgery infection onset, in fact, is higher within 3 h after oral surgery.
2004
- HSP 27 as possible prognostic factor in patients with oral squamous cell carcinoma.
[Articolo su rivista]
Lo Muzio, L; Leonardi, R; Mariggiò, Ma; Mignogna, Md; Rubini, C; Vinella, A; Pannone, G; Giannetti, Luca; Serpico, R; Testa, Nf; De Rosa, G; Staibano, S.
abstract
HSP27 belongs to the Heat shock protein (HSP) family, which plays essential functions in cells under physiological conditions and prevents stress-induced cellular damage. The aim of this study was to investigate the biological role of HSP27 in oral tumorigenesis.MATERIALS AND METHODS: Seventy-nine cases of oral squamous cell carcinoma and 10 cases of normal mucosa were analysed for HSP27 expression by immunohistochemistry. Moreover, the western blot analysis was performed on two cases of normal mucosa and five cases of OSCC.RESULTS: Normal oral mucosa showed a suprabasal expression of HSP27. Twenty-four cases of SCC (30.7%) showed a diffuse staining for HSP27, and 48 cases (60.3%) showed instead a decrease in staining, which was diffuse, homogeneous, or with alternation of positive and negative areas in a single tumor ("mosaic" pattern). Only 7 cases of OSCC (7.5%) were completely negative for HSP27. Frequency of lymph node metastases was higher in HSP27-negative tumours (3/7, 42.8%) than in HSP-reduced (16/48, 33.3%) or positive ones (5/26, 19.2%). Regard staging, stages I and II had a higher score than stages III and IV (stage I > stage II > stage III > stage IV). There was also a statistically significant correlation between HSP27 expression and grade: HSP27 expression was reduced in poorly differentiated tumours (P < 0.05). When analysed for prognostic significance, patients with negative/reduced HSP27 expression had poorer survival rates than the group with positive HSP27 expression (P < 0.05). The statistical analysis of these findings showed no significant correlation between HSP27 expression, sex, and tumour size.CONCLUSION: Cases with reduced expression were more aggressive and poorly differentiated. These data suggest that HSP27 expression may be useful in order to identify cases of oral squamous cell carcinoma with more aggressive and invasive phenotype providing novel diagnostic and prognostic information on individual patient survival with oral cancers
2004
- Possibilità di riabilitazione protesica nei traumi mascellari
[Abstract in Rivista]
Giannetti, Luca; Generali, Luigi; Bortolini, Sergio; Bellini, Pierantonio; Consolo, Ugo
abstract
Vedasi l'allegato
2004
- Sterss nel paziente odontoiatrico
[Articolo su rivista]
Barbieri, Alberto; Ghirardini, A. M.; Pinna, C.; Giannetti, L.; Genazzani, Alessandro
abstract
...
2004
- Utilizzo di calvaria per riabilitazione impianto-protesica della mandibola edentula: descrizione di un caso clinico
[Abstract in Rivista]
Bellini, Pierantonio; Generali, Luigi; Giannetti, Luca; Bortolini, Sergio; Consolo, Ugo
abstract
Vedsai l'allegato
2003
- Anomalie ereditarie dei denti e della mucosa orale in sindromi complesse caratterizzate da iper o ipotricosi
[Articolo su rivista]
Giannetti, Luca; Consolo, Ugo; Bambini, F.
abstract
descrizione clinica di anomalie ereditarie degli elemnti dentali e della mucosa del cavo orale in pazienti sindromici con ipo e iper tricosi
2003
- Oral melanoma and oral naevi: clinical and diagnostic aspects.
[Articolo su rivista]
Giannetti, Luca; Consolo, Ugo; Rappelli, G.; Petruzzi, M.; De Benedettis, M.
abstract
Vedasi l'allegato
2003
- Teeth and oral mucosa in neurocutaneous syndromes, metabolic diseases and in diseases with defects of DNA repair [La mucosa orale e i denti in sindromi neurocutanee, malattie metaboliche e nelle malattie caratterizzate da difetti di riparo del DNA.]
[Articolo su rivista]
Giannetti, Luca; Bambini, F.; Consolo, Ugo
abstract
Oral mucosa is frequently involved in a group of genetic diseases, which affect the skin and other organs, particularly the central nervous system. The lesions may be of characterized by inflammations in neurocutaneous syndromes and by tumoral lesions in those diseases with defects of DNA repair. The teeth are mainly involved in progeria, while jaw keratocysts are highly characteristic in Gorlin's syndrome.
2003
- Valutazione scintigrafica con metodica SPECT dell'effetto dei bifosfonati sul processo di osteointegrazione implantare.
[Articolo su rivista]
Bambini, F.; De Stefano, C. A.; Giannetti, Luca; Memè, L.; Pellecchia, M.
abstract
nel presente lavoro si descrive l'azione dei bifosfonati assunti per via orale da pazienti trattati con terapia implantare orale e valutati con metodica scintigrafica
2003
- [Tooth disorders in ectodermal dysplasias]
[Articolo su rivista]
Giannetti, Luca; G., Rapelli; Consolo, Ugo
abstract
Recently, the molecular bases of the most frequent ectodermal dysplasias have been identified; they involve genes responsible for the epithelial morphogenesis, and the regulation of cell survival and proliferation. Teeth alterations with characteristic features are often observed in X-linked anhidrotic ectodermic dysplasia and in autosomic recessive anhidrotic ectoderma, rarely in hidrotic ectodermal dysplasia.
2003
- valutazione morfologica in microscopia elettronica a scansione di differenti tecniche di rimozione del tessuto dentale
[Articolo su rivista]
Massaccesi, C.; Rappelli, G.; Giannetti, Luca; Putignano, A.; Di Cristoforo, A.
abstract
Il presente lavoro valuta con metodica in microscopia elettronica a scansione la morfologia del tessuto dentinale a seguito di rimozione.
2002
- Immunità della mucosa orale.
[Articolo su rivista]
Giannetti, Luca; Rappelli, G.; Gatto, R.; Consolo, Ugo
abstract
Vedasi allegato
2002
- La sindrome orale allergica ( SOA ). Osservazioni su sei casi
[Articolo su rivista]
Giannetti, Luca; Motolese, A.; Gatto, R.; Consolo, Ugo
abstract
Vedasi l'allegato
2002
- Patologie della mucosa orale ed anomalie dentarie nelle epidermolisi bollosa acquisita (EBA) e nella dermatite bollosa a IGA lineare.
[Articolo su rivista]
Giannetti, Luca; Consolo, Ugo; Gatto, R.; Bambini, F.
abstract
Vedasi l'allegato
2001
- Adenomatoid odontogenic tumor. A case report
[Articolo su rivista]
Figurelli, Sabina; Pollastri, G; Giannetti, Luca; Chiarini, Luigi
abstract
The adenomatoid odontogenic tumor is a benign bony lesion of the maxilla and mandible, it represents 3% of all odontogenic tumors, and is more frequent in females in their second decade of life. It affects mainly the maxilla associated with embedded teeth, often canines, but it also occurs in the mandible, especially in the anterior region. It originates from epithelial cells of the dental lamina complex system, but the histologic feature with gland-like structures explains its name and classification. Clinically silent, it is often discovered during radiological examinations as a well defined unilocular radiolucent image. The definitive diagnosis is obtained by histological examinations, which allow the differential diagnosis from other bony lesions. Treatment must include close examinations, such as axial and coronal CT scanning and eventually 3D reconstruction. Histological examination with a preoperative biopsy suggests a conservative surgical treatment consisting of a simple enucleation for the low incidence of recurrence. A clinical case is presented with peculiar features different from that reported in letterature.
2000
- Intracranial spread of a giant frontal mucocele: case report.
[Articolo su rivista]
Chiarini, Luigi; Nocini, P. F.; Bedogni, A.; Consolo, Ugo; Giannetti, Luca; Merli, G. A.
abstract
A giant mucocele eroded both the anterior and posterior wall of the frontal sinus and infiltratedthe dura mater. Its extracranial growth caused a frontal bony prominence. The tumour and part of the durawere resected. A 126 cm defect in the dura was repaired with a freeze-dried patch. A split-thickness bonegraft from the right parietal region was used to repair the anterior frontal bony defect. The result one yearlater was satisfactory. Spiral computed tomography with three-dimensional reconstructions excluded anyrecurrence of the tumour and showed good integration of bone grafts. © 2000 The British Association of Oraland Maxillofacial Surgeons
2000
- Lesioni neoplastiche della mucosa orale.Testo atlante
[Monografia/Trattato scientifico]
Giannetti, Luca; Soro, E.
abstract
i tumori della mucosa orale costituiscono un capitolo di grande interesse per la elevata incidenza, l'ampio spettro delle manifestazioni cliniche, la varietà dei quadri istopatologici , l'impegno terapeutico e per la complessità biologica tipica di un'area di transizione cutaneo-mucosale, ricca di strutture differenziate.
2000
- a comparison between radial forearm flap and preliminated fasciomucosal free flap in oral recostruction
[Abstract in Rivista]
Chiarini, Luigi; Nocini, P. F.; Bedogni, A.; Giannetti, Luca; DE SANTIS, Giorgio; Consolo, Ugo
abstract
1998
- Confronto clinico-terapeutico tra due modelli bilaminari di innesto libero nel trattamento del paziente portatore di recessioni gengivali.
[Relazione in Atti di Convegno]
Bertoldi, Carlo; Galetti, Riccardo; Giannetti, Luca
abstract
Nel 1985 Langer e Langer e nel 1987 Nelson presentavano quelli che a tuttoggi rappresentano gli ultimi essenziali sviluppi delle tecniche ad innesto bilaminare per la correzione delle recessioni gengivali ampie e profonde e la correzione del "corteo" obiettivo e sintomatologico ad esse associato.
Secondo Langer e Langer l'innesto deve essere composito (epitelio-connettivale) mentre Nelson propone un innesto sottoperiostale esclusivamente connettivale.
Scopo del presente lavoro è di confrontare longitudinalmente i risultati ottenuti, in quanto a "copertura radicolare" e "induzione di gengiva cheratinizzata", con l'impiego della metodica di Langer e Langer e di quella di Nelson. Nella fattispecie, tuttavia, entrambe le metodiche sono state modificate, tentando di raggiungere una maggior ricopertura dell'innesto ed utilizzando scarichi divergenti nel primo caso, mentre si eseguiva l'innesto a "mezzo spessore" (sovraperiostale) nel secondo caso.
Sono stati selezionati 32 casi clinici dotati di sufficienti caratteristiche di standardizzazione da permettere l'accorpamente in un unico gruppo di indagine. In tale ambito era possibile riscontrare un ampio panorama recessorio (dalla singola recessione di Classe I di Miller a diverse recessioni di Classe III e IV).
Due equipe indipendenti di ricercatori valutavano le aree delle recessioni (e le loro eventuali recidive) e la quantità di gengiva cheratinizzata misurandone l'altezza.
I 32 casi clinici venivano divisi in 2 gruppi il più possibile omogenei per caratteristiche specifiche (entità delle lesioni gengivali) e generali (età, sesso, stato di salute, ecc.). Il primo sarebbe stato sottoposto a correzione delle recessioni seguendo la metodica di Nelson ed il secondo quella di Langer e Langer modificate.
Le valutazioni venivano, in entrambi i casi, condotte in fase pre-operatoria, ad un mese dall'intervento ed ad un anno dall'intervento.
Ciò creava un ulteriore suddivisione in altrettanti sottogruppi costituiti, in effetti, dagli stessi individui nelle diverse fasi di osservazione delle recessioni e della gengiva cheratinizzata.
Da un punto di vista statistico, nei confronti tra due Sottogruppi, costituiti da pazienti diversi ed entrambi a distribuzione normale, si è impiegato il test t- di Student. Nella valutazione di 2 Sottogruppi, costituiti da individui differenti di cui almeno 1 non era a distribuzione normale, si è impiegato il test non paramentrico di Mann-Whitney. Nella valutazione di più di 2 Sottogruppi, costituiti dagli stessi soggetti prima e dopo trattamenti differenti e con distribuzioni non normali, si è impiegato il test non paramentrico di Friedman, seguito, per le evidenziazioni particolari dei Sottogruppi tra cui esisteva differenza statisticamente significativa, dal test non paramentrico per la somma dei ranghi di Wilcoxon (applicabile a 2 Sottogruppi per volta).
Dato che, nell'ambito dei differenti test statistici, i vari confronti erano applicati coinvolgendo 1 dei Sottogruppi almeno 4 volte, si è impiegata la Diseguaglianza di Bonferroni per stabilire il valore di p significativo che, nella fattispecie, doveva essere inferiore a 0,0125.
L'analisi statistica dei dati mostra, senza ombra di dubbio, in entrambi i Gruppi, la presenza di una variazione statisticamente significativa (nella fattispecie indicativa di risoluzione clinica del difetto), per quanto riguarda i due parametri testati (area delle recessioni ed altezza della fascia di gengiva cheratinizzata) tra la fase di pre-intervento ed il primo controllo considerato (ad un mese dall'intervento). Per entrambi i gruppi di intervento, per quanto riguarda i risultati conseguiti come risoluzione delle aree recessorie, tali buoni risultati si mantengono stabili nella valutazione successiva ad un anno. L'altezza della gengiva cheratinizzata, invece, subisce un incremento statisticamente significativo passando dal controllo "a un mese" a quello "a un a
1998
- Gli effetti della permanenza in ambito biologico e i risultati di test standardizzati sulla ricettività corrosiva di alcuni dei più diffusi mezzi di osteosintesi e su due tipi di impianti dentali: uno studio preliminare.
[Relazione in Atti di Convegno]
Bertoldi, Carlo; Giannetti, Luca; Galetti, Riccardo; Chiarini, Luigi; Consolo, Ugo
abstract
Vedasi l'allegato
1998
- Ricostruzione post-traumatica del pavimento orbitario.
[Relazione in Atti di Convegno]
Giannetti, Luca; Bellini, Pierantonio; Consolo, Ugo
abstract
Vedasi l'allegato
1996
- Microstomia secondaria a sclerodermatomiosite: presentazione di un caso con correzione chirurgica.
[Relazione in Atti di Convegno]
Chiarini, Luigi; Bertoldi, Carlo; Giannetti, Luca
abstract
La sindrome Sclero-Dermatomiositica è una malattia cronica caratterizzata da irrigidimento ed inspessimento della cute, da anomalie dei piccoli vasi sanguigni e da fenomeni fibrotici che interessano, tra l'altro, l'apparato muscolare e numerosi organi interni quale il tratto gastrointestinale, il polmone, il cuore ed i reni.
Mentre la sindrome Sclero-Dermatomiositica sistemica è una forma patologica molto facilmente (anche se non obbligatoriamente) progressiva, esiste una forma Sclero-Dermatomiositica limitata (limited Systemic Sclerosis) che solitamente non presenta l'andamento progressivo della precedente e difficilmente condurrà a complicazioni viscerali o sistemiche.
Un quadro preciso, particolare ed assai dettagliato di accertamenti Clinico-Strumentali vengono giudicati in grado di consentire la diagnosi differenziale tra le suddette forme e definire la direzione eventualmente evolutiva di esse.
In campo Oro-Maxillo-Facciale esistono complicanze specifiche delle sindromi Sclero-Dermatomiositiche tra cui troviamo l'assottigliamento atrofico delle labbra e la microstomia secondaria.
Gli autori illustrano la procedura diagnostica corretta e dimostrano che, in caso si possa verificare una forma Sclero-Dermatomiositica limitata, l'intervento di correzione della microstomia tramite tecnica di Gillies presenta risultati soddisfacenti e stabili nel tempo.
Codice: IT\ICCU\AQ1\0020032
1995
- Microstomia da Sclero-Dermatomiosite: caso clinico
[Abstract in Atti di Convegno]
Chiarini, Luigi; Bertoldi, Carlo; Tanza, D.; Giannetti, Luca
abstract
Gli autori si propongono uno studio preliminare sulle possibilità di inquadramento clinico e trattamento chirurgico dei pazienti portatori di Sindrome Sclero-Dermatomiositica con interessamento orale.
Basandosi sui dati della letteratura applicano un protocallo atto ad individuare le forme Sclero-Dermatomiositiche non evolutive (o a lenta evoluzione).
Presentano quindi un intervento per correzione di microstomia secondaria a Sclero-Dermatomiosite riservandosi la valutazione dei risultati dello stesso nel tempo.
1995
- Osteoma mandibolare gigante: caso clinico.
[Abstract in Atti di Convegno]
Chiarini, Luigi; Bertoldi, Carlo; Tanza, D.; Giannetti, Luca
abstract
Gli autori svolgono uno studio preliminare sulle diverse possibilità di diagnosi clinica e terapia su pazienti portatori di lesione Osteomatosa.
Diversi sono i sistemi descritti in bibliografia per giungere ad una diagnosi definitiva di "neoformazione osteomatosa".
Si va dalle metodiche, quasi esclusivamente radiologiche, impiegate dagli studiosi delle forme multifocali ereditarie ai sistemi imperniati esclusivamente sull'istologia (considerata l'unico esame dirimente) del pezzo asportato sostenuti dagli anatomo-patologi.
Gli autori propongono una metodica valutativa più completa ed adattabile alla clinica del soggetto e su questa base eseguono un trattamento chirurgico conservativo su un paziente latore di una notevole massa osteomatosa riservandosi la valutazione longitudinale dell'intervento.